Microparticles, microcapsules and microspheres: A review of recent developments and prospects for oral delivery of insulin
CY Wong, H Al-Salami, CR Dass - International journal of pharmaceutics, 2018 - Elsevier
Diabetes mellitus is a chronic metabolic health disease affecting the homeostasis of blood
sugar levels. However, subcutaneous injection of insulin can lead to patient non …
sugar levels. However, subcutaneous injection of insulin can lead to patient non …
Sugar-lowering drugs for type 2 diabetes mellitus and metabolic syndrome—Review of classical and new compounds: Part-I
R Vieira, SB Souto, E Sánchez-López… - Pharmaceuticals, 2019 - mdpi.com
Diabetes mellitus (DM) is a metabolic disorder characterized by chronic hyperglycemia
together with disturbances in the metabolism of carbohydrates, proteins and fat, which in …
together with disturbances in the metabolism of carbohydrates, proteins and fat, which in …
Nanoparticle delivery systems in the treatment of diabetes complications
EB Souto, SB Souto, JR Campos, P Severino… - Molecules, 2019 - mdpi.com
Diabetes mellitus, an incurable metabolic disease, is characterized by changes in the
homeostasis of blood sugar levels, being the subcutaneous injection of insulin the first line …
homeostasis of blood sugar levels, being the subcutaneous injection of insulin the first line …
In vivo pharmacokinetics and biodistribution of resveratrol-loaded solid lipid nanoparticles for brain delivery
Resveratrol is a potent anticancer. However, because of its low half-life (< 0.25 h) the
molecule is difficult to achieve the therapeutic concentration at the site of action. The aim of …
molecule is difficult to achieve the therapeutic concentration at the site of action. The aim of …
New nanotechnologies for the treatment and repair of skin burns infections
Burn wounds are highly debilitating injuries, with significant morbidity and mortality rates
worldwide. In association with the damage of the skin integrity, the risk of infection is …
worldwide. In association with the damage of the skin integrity, the risk of infection is …
Loading, release profile and accelerated stability assessment of monoterpenes-loaded solid lipid nanoparticles (SLN)
A Zielińska, NR Ferreira, A Feliczak-Guzik… - Pharmaceutical …, 2020 - Taylor & Francis
Glycerol monostearate solid lipid nanoparticles (SLN) were produced by hot high-pressure
homogenization technique to load alpha-pinene, citral, geraniol or limonene. SLN were …
homogenization technique to load alpha-pinene, citral, geraniol or limonene. SLN were …
Sucupira oil-loaded nanostructured lipid carriers (NLC): Lipid screening, factorial design, release profile, and cytotoxicity
R Vieira, P Severino, LA Nalone, SB Souto, AM Silva… - Molecules, 2020 - mdpi.com
Essential oils are odorant liquid oily products consisting of a complex mixture of volatile
compounds obtained from a plant raw material. They have been increasingly proven to act …
compounds obtained from a plant raw material. They have been increasingly proven to act …
(+)-Limonene 1, 2-epoxide-loaded slns: Evaluation of drug release, antioxidant activity, and cytotoxicity in an HaCaT cell line
EB Souto, A Zielinska, SB Souto, A Durazzo… - International Journal of …, 2020 - mdpi.com
In this work, we developed a solid lipid nanoparticle (SLN) formulation with (+)-limonene 1, 2-
epoxide and glycerol monostearate (Lim-SLNs), stabilized with Poloxamer® 188 in aqueous …
epoxide and glycerol monostearate (Lim-SLNs), stabilized with Poloxamer® 188 in aqueous …
New glucose oxidase-immobilized stimuli-responsive dextran nanoparticles for insulin delivery
Designing strategies for the use of biopolymer-based nanoparticles as drug delivery carriers
is a considerable challenge in pharmaceutical science. Present study reports synthesis of a …
is a considerable challenge in pharmaceutical science. Present study reports synthesis of a …
Stabilization challenges and formulation strategies associated with oral biologic drug delivery systems
V Truong-Le, PM Lovalenti, AM Abdul-Fattah - Advanced drug delivery …, 2015 - Elsevier
Delivery of proteins to mucosal tissues of GI tract typically utilize formulations which protect
against proteolysis and target the mucosal tissues. Using case studies from literature and …
against proteolysis and target the mucosal tissues. Using case studies from literature and …