Natural products: An upcoming therapeutic approach to cancer
S Dutta, S Mahalanobish, S Saha, S Ghosh… - Food and Chemical …, 2019 - Elsevier
Cancer is one of the leading causes of death across the world. Different environmental and
anthropogenic factors initiate mutations in different functional genes of growth factors and …
anthropogenic factors initiate mutations in different functional genes of growth factors and …
Insulin-like growth factor 1 (IGF-1) signaling in glucose metabolism in colorectal cancer
A Kasprzak - International journal of molecular sciences, 2021 - mdpi.com
Colorectal cancer (CRC) is one of the most common aggressive carcinoma types worldwide,
characterized by unfavorable curative effect and poor prognosis. Epidemiological data re …
characterized by unfavorable curative effect and poor prognosis. Epidemiological data re …
Targeting pyruvate dehydrogenase kinase signaling in the development of effective cancer therapy
Pyruvate is irreversibly decarboxylated to acetyl coenzyme A by mitochondrial pyruvate
dehydrogenase complex (PDC). Decarboxylation of pyruvate is considered a crucial step in …
dehydrogenase complex (PDC). Decarboxylation of pyruvate is considered a crucial step in …
Resveratrol: An overview of its anti-cancer mechanisms
Cancer is one of the leading causes of death worldwide. Chemotherapy and radiotherapy
are the conventional primary treatments for cancer patients. However, most of cancer cells …
are the conventional primary treatments for cancer patients. However, most of cancer cells …
Insight into polyphenol and gut microbiota crosstalk: are their metabolites the key to understand protective effects against metabolic disorders?
M Koudoufio, Y Desjardins, F Feldman, S Spahis… - Antioxidants, 2020 - mdpi.com
Lifestyle factors, especially diet and nutrition, are currently regarded as essential avenues to
decrease modern-day cardiometabolic disorders (CMD), including obesity, metabolic …
decrease modern-day cardiometabolic disorders (CMD), including obesity, metabolic …
Combination therapy using polyphenols: An efficient way to improve antitumoral activity and reduce resistance
Polyphenols represent a structural class of mainly natural organic chemicals that contain
multiple phenol structural units. The beneficial properties of polyphenols have been …
multiple phenol structural units. The beneficial properties of polyphenols have been …
Potential therapeutic targets of resveratrol, a plant polyphenol, and its role in the therapy of various types of cancer
Cancer is among the most prominent causes of mortality worldwide. Different cancer therapy
modes employed, including chemotherapy and radiotherapy, have been reported to be …
modes employed, including chemotherapy and radiotherapy, have been reported to be …
Colorectal cancer (CRC) as a multifactorial disease and its causal correlations with multiple signaling pathways
M Wan, Y Wang, Z Zeng, B Deng, B Zhu… - Bioscience …, 2020 - portlandpress.com
Colorectal cancer (CRC) is the third most common malignancy and one of the leading
causes of cancer-related death among men worldwide. CRC is a multifactor digestive …
causes of cancer-related death among men worldwide. CRC is a multifactor digestive …
Targeting lactate metabolism and glycolytic pathways in the tumor microenvironment by natural products: A promising strategy in combating cancer
Anticancer drugs are not purely effective because of their toxicity, side effects, high cost,
inaccessibility, and associated resistance. On the other hand, cancer is a complex public …
inaccessibility, and associated resistance. On the other hand, cancer is a complex public …
Modulation of dysregulated cancer metabolism by plant secondary metabolites: A mechanistic review
Several signaling pathways and basic metabolites are responsible for the control of
metabolism in both normal and cancer cells. As emerging hallmarks of cancer metabolism …
metabolism in both normal and cancer cells. As emerging hallmarks of cancer metabolism …