Role of regulatory non-coding RNAs in traumatic brain injury

S Li, N Qiu, A Ni, MH Hamblin, KJ Yin - Neurochemistry international, 2024 - Elsevier
Traumatic brain injury (TBI) is a potentially fatal health event that cannot be predicted in
advance. After TBI occurs, it can have enduring consequences within both familial and …

[HTML][HTML] Physiological and pathological functions of circular RNAs in the nervous system

M Zhou, S Li, C Huang - Neural Regeneration Research, 2024 - journals.lww.com
Circular RNAs (circRNAs) are a class of covalently closed single-stranded RNAs that are
expressed during the development of specific cells and tissues. CircRNAs play crucial roles …

Near-infrared-IIb emitting single-atom catalyst for imaging-guided therapy of blood-brain barrier breakdown after traumatic brain injury

B Huang, T Tang, SH Chen, H Li, ZJ Sun… - Nature …, 2023 - nature.com
The blood-brain barrier breakdown, as a prominent feature after traumatic brain injury,
always triggers a cascade of biochemical events like inflammatory response and free radical …

[HTML][HTML] A novel mechanism linking ferroptosis and endoplasmic reticulum stress via the circPtpn14/miR-351-5p/5-LOX signaling in melatonin-mediated treatment of …

C Wu, M Du, R Yu, Y Cheng, B Wu, J Fu, W Tan… - Free Radical Biology …, 2022 - Elsevier
Traumatic brain injury (TBI) can lead to disability or devastating consequences with few
established treatments. Although ferroptosis has been shown to be involved in TBI, the …

A novel circular RNA, circIgfbp2, links neural plasticity and anxiety through targeting mitochondrial dysfunction and oxidative stress-induced synapse dysfunction after …

M Du, C Wu, R Yu, Y Cheng, Z Tang, B Wu, J Fu… - Molecular …, 2022 - nature.com
Traumatic brain injury (TBI) can lead to different neurological and psychiatric disorders.
Circular RNAs (circRNAs) are highly expressed in the nervous system and enriched in …

Near-infrared-IIb fluorescent nanozymes for imaging-guided treatment of traumatic brain injury

F Liu, B Huang, T Tang, F Wang, R Cui, M Zhang… - Chemical Engineering …, 2023 - Elsevier
Traumatic brain injury (TBI) often results in damage to the blood–brain barrier (BBB), leading
to secondary effects such as neuroinflammation mediated by reactive oxygen species …

CircSpna2 attenuates cuproptosis by mediating ubiquitin ligase Keap1 to regulate the Nrf2‐Atp7b signalling axis in depression after traumatic brain injury in a mouse …

M Du, J Fu, J Zhang, Z Zhu, X Huang… - Clinical and …, 2024 - Wiley Online Library
Background Depression is a common but often overlooked consequence in individuals with
post‐traumatic brain injury (TBI). Circular RNAs (circRNAs) play essential roles in the …

From static to dynamic: live observation of the support system after ischemic stroke by two photon-excited fluorescence laser-scanning microscopy

X Wu, JR Li, Y Fu, DY Chen, H Nie… - Neural Regeneration …, 2023 - journals.lww.com
Ischemic stroke is one of the most common causes of mortality and disability worldwide.
However, treatment efficacy and the progress of research remain unsatisfactory. As the …

Protective effects and regulatory pathways of melatonin in traumatic brain injury mice model: Transcriptomics and bioinformatics analysis

J Fu, Q Zhou, B Wu, X Huang, Z Tang, W Tan… - Frontiers in Molecular …, 2022 - frontiersin.org
Traumatic brain injury (TBI) is the leading cause of disability and mortality globally.
Melatonin (Mel) is a neuroendocrine hormone synthesized from the pineal gland that …

Non-coding RNAs in the regulation of blood–brain barrier functions in central nervous system disorders

P Sun, MH Hamblin, KJ Yin - Fluids and barriers of the CNS, 2022 - Springer
The blood–brain barrier (BBB) is an essential component of the neurovascular unit that
controls the exchanges of various biological substances between the blood and the brain …