Vertebrate and Invertebrate Animal and New In Vitro Models for Studying Neisseria Biology

MM Girgis, M Christodoulides - Pathogens, 2023 - mdpi.com
The history of Neisseria research has involved the use of a wide variety of vertebrate and
invertebrate animal models, from insects to humans. In this review, we itemise these models …

Human infection challenge in the pandemic era and beyond, HIC-Vac annual meeting report, 2022

MVC Barnes, A Mandla, E Smith… - Immunotherapy …, 2023 - academic.oup.com
HIC-Vac is an international network of researchers dedicated to developing human infection
challenge studies to accelerate vaccine development against pathogens of high global …

A Randomized Controlled Clinical Trial of Nasal Immunization with Live Virulence Attenuated Streptococcus pneumoniae Strains Using Human Infection Challenge

H Hill, E Mitsi, E Nikolaou, A Blizard… - American Journal of …, 2023 - atsjournals.org
Rationale: Pneumococcal pneumonia remains a global health problem. Pneumococcal
colonization increases local and systemic protective immunity, suggesting that nasal …

Tackling immunosuppression by Neisseria gonorrhoeae to facilitate vaccine design

RA Jones, F Ramirez-Bencomo, G Whiting… - PLoS …, 2024 - journals.plos.org
Gonorrhoea, caused by Neisseria gonorrhoeae, is a common sexually transmitted infection.
Increasing multi-drug resistance and the impact of asymptomatic infections on sexual and …

[HTML][HTML] A questionnaire-based study exploring participant perspectives in a perinatal human challenge trial

JHJ Bevan, AA Theodosiou, J Corner… - The Pediatric …, 2023 - journals.lww.com
Background: Pregnant women have historically been excluded from most medical research,
including human challenge studies. The proof-of-concept Lactamica 9 human challenge …

Insights from targeting transferrin receptors to develop vaccines for pathogens of humans and food production animals

NF Ewasechko, S Chaudhuri… - Frontiers in Cellular and …, 2023 - frontiersin.org
While developing vaccines targeting surface transferrin receptor proteins in Gram-negative
pathogens of humans and food production animals, the common features derived from their …

[HTML][HTML] Antibodies against Neisseria meningitidis serogroups A, C, W and Y in serum and saliva of Norwegian adolescents

SV Watle, B Børud, I Laake, M Baranowska-Hustad… - Vaccine, 2023 - Elsevier
Introduction The incidence of invasive meningococcal disease (IMD) among Norwegian 16–
19-year-olds was 1–7/100,000 in the decade before the COVID-19 pandemic, with …

[PDF][PDF] Controlled human infection in late pregnancy: a single-arm interventional pilot trial investigating 3 mother-to-infant ransmission of Neisseria lactamica

AA Theodosiou, D Bogaert, DW Clearly… - The Lancet …, 2024 - eprints.soton.ac.uk
The infant respiratory microbiome is derived largely from its mother and is associated with 3
downstream health and disease. Manipulating maternal respiratory flora peripartum to 4 …

Vaccine-preventable diseases in childhood, adolescence, and young adulthood in Iceland–rotavirus, meningococci, and influenza: Room for improvements?

Í Kristinsdóttir - 2023 - opinvisindi.is
Vaccines are among the most important medical discoveries ever made and are the
cornerstone of public health interventions. Public health authorities must be attentive to the …

Caractérisation de la nucléase SSNA: un régulateur des transferts horizontaux de gènes et déterminant de la virulence de Neisseria meningitidis

M Chenal - 2023 - search.proquest.com
Les bactéries du genre Neisseria sont un exemple remarquable d'évolution et d'adaptation.
Composées principalement d'espèces commensales, seules deux espèces sont …