[HTML][HTML] Emerging innate biological properties of nano-drug delivery systems: A focus on PAMAM dendrimers and their clinical potential

H Kheraldine, O Rachid, AM Habib… - Advanced drug delivery …, 2021 - Elsevier
Drug delivery systems or vectors are usually needed to improve the bioavailability and
effectiveness of a drug through improving its pharmacokinetics/pharmacodynamics at an …

NF-κB in acute pancreatitis: Mechanisms and therapeutic potential

A Jakkampudi, R Jangala, BR Reddy, S Mitnala… - Pancreatology, 2016 - Elsevier
The incidence of acute pancreatitis (AP) is increasing globally and mortality could be high
among patients with organ failure and infected necrosis. The predominant factors …

Immunomodulatory nanosystems for treating inflammatory diseases

N Ahamad, A Kar, S Mehta, M Dewani, V Ravichandran… - Biomaterials, 2021 - Elsevier
Inflammatory disease (ID) is an umbrella term encompassing all illnesses involving chronic
inflammation as the central manifestation of pathogenesis. These include, inflammatory …

Microenvironment of pancreatic inflammation: calling for nanotechnology for diagnosis and treatment

L Liu, Y Zhang, X Li, J Deng - Journal of Nanobiotechnology, 2023 - Springer
Acute pancreatitis (AP) is a common and life-threatening digestive disorder. However, its
diagnosis and treatment are still impeded by our limited understanding of its etiology …

Targeted nanosystems: Advances in targeted dendrimers for cancer therapy

H Yang - Nanomedicine: Nanotechnology, Biology and Medicine, 2016 - Elsevier
Dendrimers possess discrete highly compact nanostructures constituted of successive
branched layers. Soon after the inception of dendrimers, recognition of their tunable …

Dendrimers for anticancer drug delivery

PK Tripathi, S Tripathi - Pharmaceutical applications of dendrimers, 2020 - Elsevier
Cancer is dreadful disease in today's world that kills millions of people every year. It is one of
the major health concerns of the 21st century. Normal chemotherapy fails to fight cancer due …

Preparation of gastrodin‐modified dendrimer‐entrapped gold nanoparticles as a drug delivery system for cerebral ischemia–reperfusion injury

W Huang, L Wang, Y Zou, X Ding, X Geng… - Brain and …, 2022 - Wiley Online Library
Objective This study sought to evaluate the feasibility of multifunctional gastrodin (GAS)‐
containing nano‐drug carrier system against cerebral ischemia–reperfusion injury (CIRI) …

Nanocarriers targeting the diseases of the pancreas

N Demirtürk, E Bilensoy - European Journal of Pharmaceutics and …, 2022 - Elsevier
Diseases of the pancreas include acute and chronic pancreatitis, exocrine pancreatic
insufficiency, diabetes and pancreatic cancer. These pathologies can be difficult to treat due …

Phosphorus-Based Dendrimer ABP Treats Neuroinflammation by Promoting IL-10-Producing CD4+ T Cells

M Hayder, M Varilh, CO Turrin, A Saoudi… - …, 2015 - ACS Publications
Dendrimers are polyfunctional nano-objects of perfectly defined structure that can provide
innovative alternatives for the treatment of chronic inflammatory diseases, including multiple …

[HTML][HTML] A mini-review of diagnostic and therapeutic nano-tools for pancreatitis

Q Zhang, S Li, Y Yu, Y Zhu, R Tong - International Journal of …, 2022 - ncbi.nlm.nih.gov
Pancreatitis is an inflammatory reaction of pancreatic tissue digestion, edema, bleeding and
even necrosis caused by activation of pancreatin due to various causes. In particular …