Bacterial exo-polysaccharides in biofilms: role in antimicrobial resistance and treatments

S Singh, S Datta, KB Narayanan… - Journal of Genetic …, 2021 - Springer
Background Bacterial biofilms are aggregation or collection of different bacterial cells which
are covered by self-produced extracellular matrix and are attached to a substratum …

Regulatory mechanisms of exopolysaccharide synthesis and biofilm formation in Streptococcus mutans

T Zheng, M Jing, T Gong, J Yan, X Wang… - Journal of Oral …, 2023 - Taylor & Francis
Background Dental caries is a chronic, multifactorial and biofilm-mediated oral bacterial
infection affecting almost every age group and every geographical region. Streptococcus …

Nanoparticles for the treatment of oral biofilms: current state, mechanisms, influencing factors, and prospects

C Hu, LL Wang, YQ Lin, HM Liang… - Advanced …, 2019 - Wiley Online Library
Due to their excellent size, designability, and outstanding targeted antibacterial effects,
nanoparticles have become a potential option for controlling oral biofilm‐related infections …

Inhibition of multidrug efflux pumps belonging to the major facilitator superfamily in bacterial pathogens

MF Varela, J Stephen, D Bharti, M Lekshmi, S Kumar - Biomedicines, 2023 - mdpi.com
Bacterial pathogens resistant to multiple structurally distinct antimicrobial agents are
causative agents of infectious disease, and they thus constitute a serious concern for public …

Strategies for combating antibiotic resistance in bacterial biofilms

KE Grooters, JC Ku, DM Richter, MJ Krinock… - Frontiers in Cellular …, 2024 - frontiersin.org
Biofilms, which are complexes of microorganisms that adhere to surfaces and secrete
protective extracellular matrices, wield substantial influence across diverse domains such as …

Bacterial-derived extracellular polysaccharides reduce antimicrobial susceptibility on biotic and abiotic surfaces

JGS Souza, BEC Oliveira, RC Costa, K Bechara… - Archives of Oral …, 2022 - Elsevier
Objective Extracellular biofilm matrix plays a role in reducing bacterial susceptibility against
antimicrobials. Since the surface where biofilm is growing modulates microbial accumulation …

The role and relationship with efflux pump of biofilm formation in Klebsiella pneumoniae

M Tang, X Wei, X Wan, Z Ding, Y Ding, J Liu - Microbial Pathogenesis, 2020 - Elsevier
This study aimed to identify the role and relationship with efflux pump of biofilm formation in
Klebsiella pneumoniae. Sixty-one K. pneumoniae clinical isolates were collected between …

Anti-Bacterial and Anti-Biofilm Activities of Anandamide against the Cariogenic Streptococcus mutans

G Wolfson, RV Sionov, R Smoum, M Korem… - International Journal of …, 2023 - mdpi.com
Streptococcus mutans is a cariogenic bacterium in the oral cavity involved in plaque
formation and dental caries. The endocannabinoid anandamide (AEA), a naturally occurring …

[HTML][HTML] Anti-bacterial and anti-biofilm activities of arachidonic acid against the cariogenic bacterium Streptococcus mutans

M Chamlagain, J Hu, RV Sionov… - Frontiers in …, 2024 - frontiersin.org
Streptococcus mutans is a Gram-positive, facultative anaerobic bacterium, which causes
dental caries after forming biofilms on the tooth surface while producing organic acids that …

Transcriptomic Stress Response in Streptococcus mutans following Treatment with a Sublethal Concentration of Chlorhexidine Digluconate

D Muehler, X Mao, S Czemmel, J Geißert, C Engesser… - Microorganisms, 2022 - mdpi.com
Despite the widespread use of antiseptics such as chlorhexidine digluconate (CHX) in
dental practice and oral care, the risks of potential resistance toward these antimicrobial …