Diagnosis of Ebola virus disease: past, present, and future

MJ Broadhurst, TJG Brooks… - Clinical microbiology …, 2016 - Am Soc Microbiol
Laboratory diagnosis of Ebola virus disease plays a critical role in outbreak response efforts;
however, establishing safe and expeditious testing strategies for this high-biosafety-level …

[HTML][HTML] Post-exposure treatments for Ebola and Marburg virus infections

RW Cross, CE Mire, H Feldmann… - Nature Reviews Drug …, 2018 - nature.com
The filoviruses—Ebola virus and Marburg virus—cause lethal haemorrhagic fever in
humans and non-human primates (NHPs). Filoviruses present a global health threat both as …

[PDF][PDF] Towards an artificial intelligence framework for data-driven prediction of coronavirus clinical severity

X Jiang, M Coffee, A Bari, J Wang, X Jiang… - … , Materials & Continua, 2020 - researchgate.net
The virus SARS-CoV2, which causes coronavirus disease (COVID-19) has become a
pandemic and has spread to every inhabited continent. Given the increasing caseload, there …

A randomized, controlled trial of ZMapp for Ebola virus infection

Prevail II Writing Group - New England Journal of Medicine, 2016 - Mass Medical Soc
Background Data from studies in nonhuman primates suggest that the triple monoclonal
antibody cocktail ZMapp is a promising immune-based treatment for Ebola virus disease …

[HTML][HTML] Transcriptomic signatures differentiate survival from fatal outcomes in humans infected with Ebola virus

X Liu, E Speranza, C Muñoz-Fontela, S Haldenby… - Genome biology, 2017 - Springer
Abstract Background In 2014, Western Africa experienced an unanticipated explosion of
Ebola virus infections. What distinguishes fatal from non-fatal outcomes remains largely …

Heterogeneities in the case fatality ratio in the West African Ebola outbreak 2013–2016

T Garske, A Cori, A Ariyarajah… - … of the Royal …, 2017 - royalsocietypublishing.org
The 2013–2016 Ebola outbreak in West Africa is the largest on record with 28 616
confirmed, probable and suspected cases and 11 310 deaths officially recorded by 10 June …

Strengthening health systems while responding to a health crisis: lessons learned by a nongovernmental organization during the Ebola virus disease epidemic in …

C Cancedda, SM Davis, KL Dierberg… - The Journal of …, 2016 - academic.oup.com
An epidemic of Ebola virus disease (EVD) beginning in 2013 has claimed an estimated 11
310 lives in West Africa. As the EVD epidemic subsides, it is important for all who …

[HTML][HTML] Outbreak of Ebola virus disease in the Democratic Republic of the Congo, April–May, 2018: an epidemiological study

A Barry, S Ahuka-Mundeke, YA Ahmed, Y Allarangar… - The Lancet, 2018 - thelancet.com
Summary Background On May 8, 2018, the Government of the Democratic Republic of the
Congo reported an outbreak of Ebola virus disease in Équateur Province in the northwest of …

[HTML][HTML] Machine-learning prognostic models from the 2014–16 Ebola outbreak: data-harmonization challenges, validation strategies, and mHealth applications

A Colubri, MA Hartley, M Siakor, V Wolfman… - …, 2019 - thelancet.com
Background Ebola virus disease (EVD) plagues low-resource and difficult-to-access
settings. Machine learning prognostic models and mHealth tools could improve the …

[HTML][HTML] Transforming clinical data into actionable prognosis models: machine-learning framework and field-deployable app to predict outcome of Ebola patients

A Colubri, T Silver, T Fradet, K Retzepi… - PLoS neglected …, 2016 - journals.plos.org
Background Assessment of the response to the 2014–15 Ebola outbreak indicates the need
for innovations in data collection, sharing, and use to improve case detection and treatment …