Information retrieval and text mining technologies for chemistry

M Krallinger, O Rabal, A Lourenco, J Oyarzabal… - Chemical …, 2017 - ACS Publications
Efficient access to chemical information contained in scientific literature, patents, technical
reports, or the web is a pressing need shared by researchers and patent attorneys from …

PubMed and beyond: a survey of web tools for searching biomedical literature

Z Lu - Database, 2011 - academic.oup.com
The past decade has witnessed the modern advances of high-throughput technology and
rapid growth of research capacity in producing large-scale biological data, both of which …

Linking genes to literature: text mining, information extraction, and retrieval applications for biology

M Krallinger, A Valencia, L Hirschman - Genome biology, 2008 - Springer
Efficient access to information contained in online scientific literature collections is essential
for life science research, playing a crucial role from the initial stage of experiment planning …

Literature mining in support of drug discovery

P Agarwal, DB Searls - Briefings in bioinformatics, 2008 - academic.oup.com
The drug discovery enterprise provides strong drivers for data integration. While attention in
this arena has tended to focus on integration of primary data from omics and other large …

NMDA receptors are not alone: dynamic regulation of NMDA receptor structure and function by neuregulins and transient cholesterol-rich membrane domains leads to …

A Schrattenholz, V Soskic - Current topics in medicinal …, 2006 - ingentaconnect.com
Glutamate receptors of the N-methyl-D-asparate (NMDA-) subtype are tetrameric allosteric
and ligand-gated calcium channels. They are modulated by a variety of endogenous ligands …

How Human Embryonic Stem Cell Research Can Impact In‐Vitro Drug Screening Technologies of the Future

A Schrattenholz, M Klemm - Drug testing in vitro: breakthroughs …, 2006 - Wiley Online Library
8 How Human Embryonic Stem Cell Research Can Impact In-Vitro Drug Screening
Technologies 208 autoantigen myelin oligodendrocyte glycoprotein (MOG-EAE)[17–19] as …

Comparative analysis of Rac1 binding efficiency with different classes of ligands: morpholines, flavonoids and imidazoles

N Maggi, P Arrigo, C Ruggiero - IEEE Transactions on …, 2012 - ieeexplore.ieee.org
The focal adhesion pathway has a great impact on cellular growth and survival. Its
disregulation is correlated with the loss of cellular mechanical properties. Such modifications …

[PDF][PDF] Aprimorando processos de imputação multivariada de dados com workflows

R Castaneda, C Ferlin, R Goldschmidt… - Proceedings of the …, 2008 - researchgate.net
Abstract Knowledge discovery in databases usually face the problem of missing values.
Thus there are several preprocessing mechanisms that aim to make data imputation …

Automating diseases diagnosis in human: A Time Series Analysis

J Manicassamy, P Dhavachelvan - Proceedings of the International …, 2010 - dl.acm.org
Today, there is profound vast development in merging biology with computational since,
biological data's has been predictable in an unpredictable rate. Various tools, application …

Development: multiscale CSB—simulation tools

A Prokop, S Michelson, A Prokop… - Systems Biology in Biotech …, 2012 - Springer
In order to cover bottom-up and top-down phenomena multiscale SB simulation tools should
include organ-level considerations, and should be used in conjunction with multiscale …