Protein assembly by design

J Zhu, N Avakyan, A Kakkis, AM Hoffnagle… - Chemical …, 2021 - ACS Publications
Proteins are nature's primary building blocks for the construction of sophisticated molecular
machines and dynamic materials, ranging from protein complexes such as photosystem II …

Hierarchical materials from high information content macromolecular building blocks: construction, dynamic interventions, and prediction

L Shao, J Ma, JL Prelesnik, Y Zhou, M Nguyen… - Chemical …, 2022 - ACS Publications
Hierarchical materials that exhibit order over multiple length scales are ubiquitous in nature.
Because hierarchy gives rise to unique properties and functions, many have sought …

[HTML][HTML] Hybrid nanostructures from the self-assembly of proteins and DNA

N Stephanopoulos - Chem, 2020 - cell.com
Proteins and DNA are two commonly used molecules for self-assembling nanotechnology.
In this tutorial review, we discuss the hybrid field of" protein-DNA nanotechnology," whereby …

Spatially patterned, porous protein crystals as multifunctional materials

K Han, Z Zhang, FA Tezcan - Journal of the American Chemical …, 2023 - ACS Publications
While the primary use of protein crystals has historically been in crystallographic structure
determination, they have recently emerged as promising materials with many advantageous …

Thermoresponsive Micellar Assembly Constructed from a Hexameric Hemoprotein Modified with Poly(N-isopropylacrylamide) toward an Artificial Light-Harvesting …

S Hirayama, K Oohora, T Uchihashi… - Journal of the American …, 2020 - ACS Publications
Artificial protein assemblies inspired by nature have significant potential in development of
emergent functional materials. In order to construct an artificial protein assembly, we …

Biomaterial‐interrelated bacterial sweeper: simplified self‐assembled octapeptides with double‐layered Trp zipper induces membrane destabilization and bacterial …

Y Fang, Y Zhu, L Li, Z Lai, N Dong, A Shan - Small Methods, 2021 - Wiley Online Library
Abstract Treatment of microbial‐associated infections continues to be hampered by impaired
antibacterial efficiency and the variability in nanomedicines. Herein, an octapeptide library …

Tunable and cooperative thermomechanical properties of protein–metal–organic frameworks

JB Bailey, FA Tezcan - Journal of the American Chemical Society, 2020 - ACS Publications
We recently introduced protein–metal–organic frameworks (protein-MOFs) as chemically
designed protein crystals, composed of ferritin nodes that predictably assemble into 3D …

Protein materials engineering with DNA

JR McMillan, OG Hayes, PH Winegar… - Accounts of chemical …, 2019 - ACS Publications
Conspectus Proteins are a class of nanoscale building block with remarkable chemical
complexity and sophistication: their diverse functions, shapes, and symmetry as well as …

Redefining protein interfaces within protein single crystals with DNA

BE Partridge, PH Winegar, Z Han… - Journal of the American …, 2021 - ACS Publications
Proteins are exquisite nanoscale building blocks: molecularly pure, chemically addressable,
and inherently selective for their evolved function. The organization of proteins into single …

Encoding hierarchical assembly pathways of proteins with DNA

OG Hayes, BE Partridge… - Proceedings of the …, 2021 - National Acad Sciences
The structural and functional diversity of materials in nature depends on the controlled
assembly of discrete building blocks into complex architectures via specific, multistep …