Electronic MEMS for triggered delivery

ACR Grayson, RS Shawgo, Y Li, MJ Cima - Advanced drug delivery …, 2004 - Elsevier
Implantable electronic devices such as pacemakers and neural implants are often used for
electrical stimulation. The usage of microfabrication techniques to produce …

Optimisation of treatment by applying programmable rate-controlled drug delivery technology

YW Chien, S Lin - Clinical pharmacokinetics, 2002 - Springer
A number of programmable rate-controlled drug delivery technologies have been developed
during the last two decades with the aim of regulating the rate of drug delivery, sustaining …

Platelet factor 4 regulates megakaryopoiesis through low-density lipoprotein receptor–related protein 1 (LRP1) on megakaryocytes

MP Lambert, Y Wang, KH Bdeir… - Blood, The Journal …, 2009 - ashpublications.org
Abstract Platelet factor 4 (PF4) is a negative regulator of megakaryopoiesis, but its
mechanism of action had not been addressed. Low-density lipoprotein (LDL) receptor …

Nicotine and cotinine increases the brain penetration of saquinavir in rat

VK Manda, RK Mittapalli, KA Bohn… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 115, 1495–1507. Abstract Endothelial tight junctions and efflux
transporters of the blood–brain barrier (BBB) significantly limit brain accumulation of many …

Chronic exposure to nicotine and saquinavir decreases endothelial Notch‐4 expression and disrupts blood‐brain barrier integrity

VK Manda, RK Mittapalli, WJ Geldenhuys… - Journal of …, 2010 - Wiley Online Library
J. Neurochem.(2010) 115, 515–525. Abstract Since the advent of HAART, there have been
substantial improvements in HIV patient survival; however, the prevalence of HIV associated …

An integrated platform for bio-analysis and drug delivery

S Amer, W Badawy - Current Pharmaceutical Biotechnology, 2005 - ingentaconnect.com
The advances in the microelectronics fabrication allow the strong appearance of micro-
electro-mechanical systems known as MEMS. MEMS enable the fabrication of smaller …

Effects of nicotine on alcohol intake in a rat model of depression

D Martı́nez-González, O Prospéro-Garcı́a… - Pharmacology …, 2002 - Elsevier
Clinical studies suggest that depression facilitates alcohol abuse. Depressed individuals
also have increased rates of smoking, and it has been suggested that nicotine may improve …

Juvenile toxicity: are we asking the right questions?

N Downes - Toxicologic pathology, 2012 - journals.sagepub.com
The recent increase in numbers of juvenile toxicity studies over the past few years has
doubtless added to our knowledge of the development of organ systems in the young …

Advances in therapeutics and delayed drug release

T Coutant, D Laniesse… - Veterinary Clinics: Exotic …, 2019 - vetexotic.theclinics.com
Medical therapy in exotic pet medicine relies widely on daily or even more frequent oral,
parenteral, or topical drug administration, which can be stressful and even harmful in some …

Drug delivery: controlled release

S Lin, Y Chien - Encyclopedia of pharmaceutical science and …, 2013 - api.taylorfrancis.com
Over the past decades, the treatment of illness has been accomplished by administering
drugs to the human body via various pharmaceutical dosage forms, like tablets. These …