Particular success has been achieved in the synthesis of new products and in processes
since the twelve principles of “green chemistry” were formulated in the 1990s. These …

The multicomponent reactions (MCRs) are emerging as environmental benign synthetic
methods of building-up of complex molecules with maximum complexity and several level of …

This review covers up to 2010 and some available references of 2011 of synthetic advances
in the Biginelli reaction, including recent mechanistic advances, new building blocks, new …

The interest in 3, 4-dihydropyrimidine-2 (1 H)-(thio) ones is increasing every day, mainly due
to their paramount biological relevance. The Biginelli reaction is the classical approach to …

The comprehensive review contains the analysis of literature data concerning reactions of
heterocyclization of aminoazoles and demonstrates the application of these types of …

Three novel families of A2B adenosine receptor antagonists were identified in the context of
the structural exploration of the 3, 4-dihydropyrimidin-2 (1 H)-one chemotype. The most …

Alternative reaction pathways for Biginelli-like cyclocondensation reactions using 3-amino-1,
2, 4-triazole as a 1, 3-binucleophile under different reaction conditions lead to several types …

The present review provides a study on the structural features, reactions, and synthetic
methodologies of pyrido [1, 2-a] pyrimidines. Thus, the synthetic procedures and organic …

Ultrasound-assisted synthesis of benzimidazo [2, 1-b] quinazolin-1 (1 H)-ones was achieved
via piperidine-catalyzed three-component reaction of 2-aminobenzimidazoles, an aromatic …

5-Aminotetrazole is a useful building block in organic synthesis, including various
multicomponent reactions (MCRs). In MCRs, 5-aminotetrazole usually plays a role of 1, 3 …