Antiarrhythmic medications have been available for nearly 100 years and remain a mainstay
in the management of atrial fibrillation (AF). Goals of therapy with the use of these drugs …

Atrial fibrillation is a highly prevalent cardiac arrhythmia and the most important cause of
embolic stroke. Although genetic studies have identified an increasing assembly of AF …

Asymptomatic atrial fibrillation (AF) is common and in view of its prognostic impact (the same
as of clinically overt AF) knowledge of the overall AF burden (defined as the amount of time …

Aims To assess the efficacy of BMS 914392 on atrial fibrillation (AF) burden reduction in 20
patients with pacemakers and paroxysmal atrial fibrillation (PAF). BMS 914392 is a potent …

Atrial Arrhythmia Conversion Trial (ACT) I, 8 ACT II, 9 ACT III, 10 CRAFT (Conversion of
Rapid Atrial Fibrillation Trial), 11 and A Phase III Superiority Study of Vernakalant Versus …

Atrial fibrillation (AF) is recognised as the most common sustained cardiac arrhythmia in
clinical practice. Ongoing drug development is aiming at obtaining atrial specific effects in …

Introduction: The main aim of current research on the field of atrial fibrillation (AF) treatment
is to find new antiarrhythmic drugs with less side effects. Areas covered: Dronedarone and …

Despite advances in catheter ablation techniques and device-based therapies for cardiac
arrhythmias, antiarrhythmic drugs remain essential components of any comprehensive …

Abstract Aims Antiarrhythmic drugs (AADs) for the treatment of atrial fibrillation (AF) are
associated with limited efficacy and adverse effects. Inhibition of the atrial current IKur …

Antiarrhythmic drugs are widely used, but are of modest efficacy and have important side
effects. However, even with the advance of catheter ablation for atrial fibrillation and …