[HTML][HTML] Biomedical features and therapeutic potential of rosmarinic acid

S Noor, T Mohammad, MA Rub, A Raza… - Archives of Pharmacal …, 2022 - Springer
For decades, the use of secondary metabolites of various herbs has been an attractive
strategy in combating human diseases. Rosmarinic acid (RA) is a bioactive phenolic …

[HTML][HTML] Perilla frutescens: A traditional medicine and food homologous plant

X Wu, S Dong, H Chen, M Guo, Z Sun, H Luo - Chinese Herbal Medicines, 2023 - Elsevier
Perilla frutescens, an annual herb of the Labiatae family, has been cultivated in China for
more than 2000 years. P. frutescens is the one of the first medicinal and edible plant …

Orcinol glucoside improves senile osteoporosis through attenuating oxidative stress and autophagy of osteoclast via activating Nrf2/Keap1 and mTOR signaling …

W Gong, M Liu, Q Zhang, Q Zhang… - Oxidative Medicine …, 2022 - Wiley Online Library
Oxidative stress and autophagy play essential roles in the development of senile
osteoporosis which is characterized by disrupted osteoclastic bone resorption and …

Rosmarinic acid nanomedicine for rheumatoid arthritis therapy: Targeted RONS scavenging and macrophage repolarization

B Lu, C Li, L Jing, F Zhuang, H Xiang, Y Chen… - Journal of Controlled …, 2023 - Elsevier
The infiltration of inflammatory cells, especially macrophages, integrated with the production
of reactive oxygen and nitrogen species (RONS) and the release of inflammatory cytokines …

[HTML][HTML] Luteolin-rich fraction from Perilla frutescens seed meal inhibits spike glycoprotein S1 of SARS-CoV-2-induced NLRP3 inflammasome lung cell inflammation …

S Dissook, S Umsumarng, S Mapoung… - Frontiers in …, 2023 - frontiersin.org
Objective The multi-systemic inflammation as a result of COVID-19 can persevere long after
the initial symptoms of the illness have subsided. These effects are referred to as Long …

[HTML][HTML] Comparative analysis of bioactive-phytochemical characteristics, antioxidants activities, and anti-inflammatory properties of selected black rice germ and bran …

S Mapoung, W Semmarath, P Arjsri… - … Food Research and …, 2023 - Springer
Black rice has numerous health benefits and one of the well-known functional foods
throughout the world. To encourage the increasing trend of the consumer interest in health …

A comprehensive review of the botany, ethnopharmacology, phytochemistry, pharmacology, toxicity and quality control of Perillae Fructus

S Liu, X Jin, Y Shang, L Wang, K Du, S Chen… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Perilla frutescens (Linnaeus) Britton, Mem. Torrey
Bot. Club 5: 277. 1894., is famous as a worldwide plant with multiple medical parts, including …

[HTML][HTML] Suppressive effects of rosmarinic acid rich fraction from perilla on oxidative stress, inflammation and metastasis ability in A549 cells exposed to PM via C-Jun …

K Pintha, W Chaiwangyen, S Yodkeeree, M Suttajit… - Biomolecules, 2021 - mdpi.com
Particulate matter from forest fires (PMFF) is an environmental pollutant causing oxidative
stress, inflammation, and cancer cell metastasis due to the presence of polycyclic aromatic …

A modified microwave hydrodistillation and simultaneous extraction in a rotating state to obtain essential oil, rosmarinic acid, and polysaccharides with sucrose …

X Yang, T Liu, M Wei, R Zhao, H Gu, J Li, F Chen… - Industrial Crops and …, 2022 - Elsevier
An improved approach was developed to obtain essential oil, rosmarinic acid, and
polysaccharides with sucrose stearate as a green additive from Perilla frutescens (L.) Britt …

[HTML][HTML] Anti-Osteoporosis Effect of Perilla frutescens Leaf Hexane Fraction through Regulating Osteoclast and Osteoblast Differentiation

K Phromnoi, S Yodkeeree, K Pintha, S Mapoung… - Molecules, 2022 - mdpi.com
Osteoporosis is the result of an imbalance in the bone-remodeling process via an increase
in osteoclastic activity and a decrease in osteoblastic activity. Our previous studies have …