Brief update on endocytosis of nanomedicines
The complexity of nanoscale interactions between biomaterials and cells has limited the
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …
realization of the ultimate vision of nanotechnology in diagnostics and therapeutics. As such …
Salmonella – the ultimate insider. Salmonella virulence factors that modulate intracellular survival
JA Ibarra, O Steele‐Mortimer - Cellular microbiology, 2009 - Wiley Online Library
Salmonella enterica serovar Typhimurium is a common facultative intracellular pathogen
that causes food‐borne gastroenteritis in millions of people worldwide. Intracellular survival …
that causes food‐borne gastroenteritis in millions of people worldwide. Intracellular survival …
Inflammatory caspases are innate immune receptors for intracellular LPS
The murine caspase-11 non-canonical inflammasome responds to various bacterial
infections. Caspase-11 activation-induced pyroptosis, in response to cytoplasmic …
infections. Caspase-11 activation-induced pyroptosis, in response to cytoplasmic …
Autophagy controls Salmonella infection in response to damage to the Salmonella-containing vacuole
CL Birmingham, AC Smith, MA Bakowski… - Journal of Biological …, 2006 - ASBMB
Salmonella enterica serovar Typhimurium (S. Typhimurium) is a facultative intracellular
pathogen that causes disease in a variety of hosts. S. Typhimurium actively invade host cells …
pathogen that causes disease in a variety of hosts. S. Typhimurium actively invade host cells …
Life on the inside: the intracellular lifestyle of cytosolic bacteria
K Ray, B Marteyn, PJ Sansonetti… - Nature Reviews …, 2009 - nature.com
Bacterial pathogens exploit a huge range of niches within their hosts. Many pathogens can
invade non-phagocytic cells and survive within a membrane-bound compartment. However …
invade non-phagocytic cells and survive within a membrane-bound compartment. However …
Galectin‐3, a marker for vacuole lysis by invasive pathogens
I Paz, M Sachse, N Dupont, J Mounier… - Cellular …, 2010 - Wiley Online Library
Shigella bacteria invade macrophages and epithelial cells and following internalization lyse
the phagosome and escape to the cytoplasm. Galectin‐3, an abundant protein in …
the phagosome and escape to the cytoplasm. Galectin‐3, an abundant protein in …
The autophagy receptor TAX1BP1 and the molecular motor myosin VI are required for clearance of salmonella typhimurium by autophagy
Autophagy plays a key role during Salmonella infection, by eliminating these pathogens
following escape into the cytosol. In this process, selective autophagy receptors, including …
following escape into the cytosol. In this process, selective autophagy receptors, including …
Targeting the hard to reach: challenges and novel strategies in the treatment of intracellular bacterial infections
NF Kamaruzzaman, S Kendall… - British journal of …, 2017 - Wiley Online Library
Infectious diseases continue to threaten human and animal health and welfare globally,
impacting millions of lives and causing substantial economic loss. The use of antibacterials …
impacting millions of lives and causing substantial economic loss. The use of antibacterials …
LPS Remodeling Triggers Formation of Outer Membrane Vesicles in Salmonella
Outer membrane vesicles (OMV) are proposed to mediate multiple functions during
pathogenesis and symbiosis. However, the mechanisms responsible for OMV formation …
pathogenesis and symbiosis. However, the mechanisms responsible for OMV formation …
Recognition of bacteria in the cytosol of mammalian cells by the ubiquitin system
AJ Perrin, X Jiang, CL Birmingham, NSY So… - Current biology, 2004 - cell.com
Recent studies have suggested the existence of innate host surveillance systems for the
detection of bacteria in the cytosol of mammalian cells [1–4]. The molecular details of how …
detection of bacteria in the cytosol of mammalian cells [1–4]. The molecular details of how …