Engineering precision nanoparticles for drug delivery
In recent years, the development of nanoparticles has expanded into a broad range of
clinical applications. Nanoparticles have been developed to overcome the limitations of free …
clinical applications. Nanoparticles have been developed to overcome the limitations of free …
Nanomaterials for T-cell cancer immunotherapy
T-cell-based immunotherapies hold promise for the treatment of many types of cancer, with
three approved products for B-cell malignancies and a large pipeline of treatments in clinical …
three approved products for B-cell malignancies and a large pipeline of treatments in clinical …
CD8+ cytotoxic T lymphocytes in cancer immunotherapy: A review
CD8+ cytotoxic T lymphocytes (CTLs) are preferred immune cells for targeting cancer.
During cancer progression, CTLs encounter dysfunction and exhaustion due to …
During cancer progression, CTLs encounter dysfunction and exhaustion due to …
Hybrid nanomaterials for cancer immunotherapy
Nano‐immunotherapy has been recognized as a highly promising strategy for cancer
treatment in recent decades, which combines nanotechnology and immunotherapy to …
treatment in recent decades, which combines nanotechnology and immunotherapy to …
Macrophage polarity in cancer: a review
M Najafi, N Hashemi Goradel… - Journal of cellular …, 2019 - Wiley Online Library
Macrophages are the most abundant cells within the tumor stroma displaying noticeable
plasticity, which allows them to perform several functions within the tumor microenvironment …
plasticity, which allows them to perform several functions within the tumor microenvironment …
Immunomodulatory nanosystems
Immunotherapy has emerged as an effective strategy for the prevention and treatment of a
variety of diseases, including cancer, infectious diseases, inflammatory diseases, and …
variety of diseases, including cancer, infectious diseases, inflammatory diseases, and …
Signal transducer and activator of transcription (STATs) proteins in cancer and inflammation: functions and therapeutic implication
Signal Transducer and Activator of Transcription (STAT) pathway is connected upstream
with Janus kinases (JAK) family protein and capable of integrating inputs from different …
with Janus kinases (JAK) family protein and capable of integrating inputs from different …
Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy
Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …
against cancers. Despite these advancements, challenges remain, particularly in the clinical …
Thirty years of cancer nanomedicine: success, frustration, and hope
L Salvioni, MA Rizzuto, JA Bertolini, L Pandolfi… - Cancers, 2019 - mdpi.com
Starting with the enhanced permeability and retention (EPR) effect discovery, nanomedicine
has gained a crucial role in cancer treatment. The advances in the field have led to the …
has gained a crucial role in cancer treatment. The advances in the field have led to the …
Contribution of regulatory T cells to cancer: A review
Regulatory T cells (Tregs) represent a low number of T‐cell population under normal
conditions, and they play key roles for maintaining immune system in homeostasis. The …
conditions, and they play key roles for maintaining immune system in homeostasis. The …