Cell adhesion molecules as targets of autoantibodies in pemphigus and pemphigoid, bullous diseases due to defective epidermal cell adhesion
JR Stanley - Advances in immunology, 1993 - Elsevier
Publisher Summary This chapter focuses on cell adhesion molecules as targets of
autoantibodies in pemphigus and pemphigoid, bullous diseases. In various autoimmune …
autoantibodies in pemphigus and pemphigoid, bullous diseases. In various autoimmune …
Catenins as mediators of the cytoplasmic functions of cadherins
BM Gumbiner, PD McCrea - Journal of Cell Science, 1993 - journals.biologists.com
The catenins are polypeptides that bind to the conserved cytoplasmic tail of cadherins and
are required for cad herin function. a-Catenin is related to vinculin and seems to be required …
are required for cad herin function. a-Catenin is related to vinculin and seems to be required …
Autoantibodies against a novel epithelial cadherin in pemphigus vulgaris, a disease of cell adhesion
M Amagai, V Klaus-Kovtun, JR Stanley - Cell, 1991 - cell.com
Pemphigus vulgaris (PV) is a life-threatening skin disease in which autoantibodies against a
keratinocyte cell surface 130 kd glycoprotein, PV antigen (PVA), cause loss of cell-cell …
keratinocyte cell surface 130 kd glycoprotein, PV antigen (PVA), cause loss of cell-cell …
A Homolog of the armadillo Protein in Drosophila (Plakoglobin) Associated with E-Cadherin
PD McCrea, CW Turck, B Gumbiner - Science, 1991 - science.org
Three cytoplasmic proteins, called catenins, bind to the cytoplasmic tail of the epithelial cell-
cell adhesion molecule E-cadherin. The complementary DNA sequence was determined for …
cell adhesion molecule E-cadherin. The complementary DNA sequence was determined for …
Adhesion of epidermal Langerhans cells to keratinocytes mediated by E-cadherin
A Tang, M Amagai, LG Granger, JR Stanley, MC Uddy - Nature, 1993 - nature.com
LANGERHANS cells (LC) are the principal accessory cells present in epidermis1. Because
LC have limited capacity for self-renewal2, epidermis is continually repopulated by as-yet …
LC have limited capacity for self-renewal2, epidermis is continually repopulated by as-yet …
Protocadherins: a large family of cadherin‐related molecules in central nervous system.
K Sano, H Tanihara, RL Heimark, S Obata… - The EMBO …, 1993 - embopress.org
Using the polymerase chain reaction, we have isolated numerous rat and human cDNAs of
which the deduced amino acid sequences are highly homologous to the sequences of the …
which the deduced amino acid sequences are highly homologous to the sequences of the …
The fat tumor suppressor gene in Drosophila encodes a novel member of the cadherin gene superfamily
PA Mahoney, U Weber, P Onofrechuk, H Biessmann… - Cell, 1991 - cell.com
Recessive lethal mutations in the fat locus of Drosophila cause hyperplastic, tumor-like
overgrowth of larval imaginal discs, defects in differentiation and morphogenesis, and death …
overgrowth of larval imaginal discs, defects in differentiation and morphogenesis, and death …
Targeted disruption of the pemphigus vulgaris antigen (desmoglein 3) gene in mice causes loss of keratinocyte cell adhesion with a phenotype similar to pemphigus …
PJ Koch, MG Mahoney, H Ishikawa… - The Journal of cell …, 1997 - rupress.org
In patients with pemphigus vulgaris (PV), autoantibodies against desmoglein 3 (Dsg3)
cause loss of cell–cell adhesion of keratinocytes in the basal and immediate suprabasal …
cause loss of cell–cell adhesion of keratinocytes in the basal and immediate suprabasal …
The vertebrate adhesive junction proteins beta-catenin and plakoglobin and the Drosophila segment polarity gene armadillo form a multigene family with similar …
Three proteins identified by quite different criteria in three different systems, the Drosophila
segment polarity gene armadillo, the human desmosomal protein plakoglobin, and the …
segment polarity gene armadillo, the human desmosomal protein plakoglobin, and the …
Autoantibodies against the amino-terminal cadherin-like binding domain of pemphigus vulgaris antigen are pathogenic.
M Amagai, S Karpati, R Prussick… - The Journal of …, 1992 - Am Soc Clin Investig
Complementary DNA cloning of the 130-kD pemphigus vulgaris (PV) autoantigen (PVA) has
indicated that it is a member of the cadherin family of Ca (2+)-dependent cell adhesion …
indicated that it is a member of the cadherin family of Ca (2+)-dependent cell adhesion …