Semiconductor quantum dots (QDs) have become important fluorescent probes for in vitro
and in vivo bioimaging research. Their nanoparticle surfaces for versatile bioconjugation …

Semiconductor quantum dots (QDs) are brightly luminescent nanoparticles that have found
numerous applications in bioanalysis and bioimaging. In this review, we highlight recent …

Effective tumor regression has been observed with chimeric antigen receptor (CAR) T cells;
however, the development of an affordable, safe, and effective CAR-T cell treatment remains …

Quantum dots (QDs) are highly fluorescent nanocrystals with advanced photophysical and
spectral properties: high brightness and stability against photobleaching accompanied by …

Iron–dextran nanoparticles functionalized with T cell activating proteins have been used to
study T cell receptor (TCR) signaling. However, nanoparticle triggering of membrane …

Artificial antigen presenting cells (aAPC), which deliver stimulatory signals to cytotoxic
lymphocytes, are a powerful tool for both adoptive and active immunotherapy. Thus far …

T cells have to detect rare high-affinity 'foreign'peptide MHC (pMHC) ligands among
abundant low-affinity 'self'-peptide MHC ligands. It remains unclear how this remarkable …

Cancer immunotherapy has recently burst onto the center stage of cancer treatment and
research. T lymphocyte adoptive cellular transfer (ACT), a form of cancer immunotherapy …

Therapeutic responses to chimeric antigen receptor (CAR) T cell therapy in patients with
limited treatment options have been appealing in several clinical trials. However, the efficacy …

TCR-dependent signaling events have been observed to occur in TCR microclusters. We
found that some TCR microclusters are present in unstimulated murine T cells, indicating …