Targeted mechanical stimulation via magnetic nanoparticles guides in vitro tissue development
AR Abdel Fattah, N Kolaitis, K Van Daele… - Nature …, 2023 - nature.com
Tissues take shape through a series of morphogenetic movements guided by local cell-
scale mechanical forces. Current in vitro approaches to recapitulate tissue mechanics rely …
scale mechanical forces. Current in vitro approaches to recapitulate tissue mechanics rely …
Engineering the physical microenvironment into neural organoids for neurogenesis and neurodevelopment
Understanding the signals from the physical microenvironment is critical for deciphering the
processes of neurogenesis and neurodevelopment. The discovery of how surrounding …
processes of neurogenesis and neurodevelopment. The discovery of how surrounding …
A controllable perfusion microfluidic chip for facilitating the development of retinal ganglion cells in human retinal organoids
J Gong, Y Gong, T Zou, Y Zeng, C Yang, L Mo, J Kang… - Lab on a Chip, 2023 - pubs.rsc.org
Retinal organoids (ROs) derived from human pluripotent stem cells (hPSCs) have become a
promising model in vitro to recapitulate human retinal development, which can be further …
promising model in vitro to recapitulate human retinal development, which can be further …
Minireview: Insights into the role of TRP channels in the retinal circulation and function
S Thébault - Neuroscience letters, 2021 - Elsevier
Consistent with their wide distribution throughout the CNS, transcripts of all transient
receptor potential (TRP) cation channel superfamily members have been detected in both …
receptor potential (TRP) cation channel superfamily members have been detected in both …
Graphene-based microfluidic perforated microelectrode arrays for retinal electrophysiological studies
Perforated microelectrode arrays (pMEAs) have become essential tools for ex vivo retinal
electrophysiological studies. pMEAs increase the nutrient supply to the explant and alleviate …
electrophysiological studies. pMEAs increase the nutrient supply to the explant and alleviate …
Incubator-independent perfusion system integrated with microfluidic device for continuous electrophysiology and microscopy readouts
R Habibey - Biofabrication, 2023 - iopscience.iop.org
Advances in primary and stem cell derived neuronal cell culture techniques and abundance
of available neuronal cell types have enabled in vitro neuroscience as a substantial …
of available neuronal cell types have enabled in vitro neuroscience as a substantial …
Machine Learning Approaches to 3D Models for Drug Screening
VA da Silva, R Sharma, E Shteinberg, V Patel… - Biomedical Materials & …, 2024 - Springer
The creation of precise, functional 3D tissues can enable effective drug screening as well as
advancements in regenerative medicine. However, the inherent limitations present during …
advancements in regenerative medicine. However, the inherent limitations present during …
[HTML][HTML] The response of retinal ganglion cells to optical defocused visual stimuli in mouse retinas
C So, T Zhang, Q Wang, C Qiu, DLA Elie… - Experimental Eye …, 2024 - Elsevier
Myopia and astigmatism are two primary types of refractive errors characterized by
inaccurate focusing images on the retina. This study aimed to investigate the response …
inaccurate focusing images on the retina. This study aimed to investigate the response …
Local actuation of organoids by magnetic nanoparticles
AR Abdel Fattah, N Kolaitis, K Van Daele, AG Rustandi… - BioRxiv, 2022 - biorxiv.org
Tissues take shape during development through a series of morphogenetic movements
guided by local cell-scale forces. While current in vitro approaches subjecting tissues to …
guided by local cell-scale forces. While current in vitro approaches subjecting tissues to …
[HTML][HTML] Single cell electrophysiological alterations under dynamic loading at ultrasonic frequencies
The use of ultrasound as a non-invasive means to modulate neuronal electrophysiological
signals in experimental in vivo and in vitro models has recently been gaining momentum …
signals in experimental in vivo and in vitro models has recently been gaining momentum …