Non-alcoholic fatty liver disease and gut microbial dysbiosis-underlying mechanisms and gut microbiota mediated treatment strategies

M Jayachandran, S Qu - Reviews in Endocrine and Metabolic Disorders, 2023 - Springer
Non-alcoholic fatty liver disease (NAFLD) is by far the most prevalent form of liver disease
worldwide. It's also the leading cause of liver-related hospitalizations and deaths …

The gut-mediated function of polyphenols: Opinions on functional food development for nonalcoholic fatty liver disease

S Chen, H Zhu, Y Luo - Current Opinion in Food Science, 2023 - Elsevier
Highlights•Polyphenols effectively intervened nonalcoholic fatty liver disease
(NAFLD).•Polyphenols improved gut-vascular barrier (GVB) permeability and gut …

Dahuang Mudan decoction repairs intestinal barrier in chronic colitic mice by regulating the function of ILC3

S Huang, X Wang, X Xie, Y Su, Z Pan, Y Li… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance Dahuang Mudan decoction (DMD) is a classic
prescription for treating intestinal carbuncle from Zhang Zhongjing's “Essentials of the …

Disruption of gut barrier integrity and host–microbiome interactions underlie MASLD severity in patients with type-2 diabetes mellitus

R Forlano, L Martinez-Gili, P Takis… - Gut …, 2024 - Taylor & Francis
Aberration of the “gut-liver axis” contributes to the development and progression of
metabolic dysfunction-associated steatotic liver disease (MASLD). Here, we use multi-omics …

Multi-omics reveals that green pea (Pisum sativum L.) hull supplementation ameliorates non-alcoholic fatty liver disease via the SHMT2/glycine/mTOR/PPAR-γ …

F Guo, H Xiong, R Tsao, X Wen, J Liu, D Chen… - Food & Function, 2023 - pubs.rsc.org
Diets rich in various active ingredients may be an effective intervention strategy for non-
alcoholic fatty liver disease (NAFLD). The green pea hull (GPH) is a processing by-product …

Screening for NAFLD—current knowledge and challenges

R Forlano, G Sigon, BH Mullish, M Yee, P Manousou - Metabolites, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of abnormal liver
function tests worldwide, with an estimated prevalence ranging between 19–46% in the …

DHA-enriched phosphatidylcholine from Clupea harengus roes regulates the gut–liver axis to ameliorate high-fat diet-induced non-alcoholic fatty liver disease

L Qian, S Tian, S Jiang, Y Tang, T Han - Food & Function, 2022 - pubs.rsc.org
In this study, the protective effect of DHA-enriched phosphatidylcholine (DHA-PC) from
Clupea harengus roes against high-fat diet (HFD)-induced non-alcoholic fatty liver disease …

Which comes first, nonalcoholic fatty liver disease or arterial hypertension?

JA Golubeva, AF Sheptulina, AY Elkina, EO Liusina… - Biomedicines, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) and arterial hypertension (AH) are widespread
noncommunicable diseases in the global population. Since hypertension and NAFLD are …

Brain-gut-liver axis: Chronic psychological stress promotes liver injury and fibrosis via gut in rats

MY Xu, CC Guo, MY Li, YH Lou, ZR Chen… - Frontiers in Cellular …, 2022 - frontiersin.org
Background The effect of chronic psychological stress on hepatitis and liver fibrosis is
concerned. However, its mechanism remains unclear. We investigated the effect and …

The role of long noncoding RNAs in intestinal health and diseases: a focus on the intestinal barrier

Q Lu, Y Liang, X Meng, Y Zhao, H Fan, S Hou - Biomolecules, 2023 - mdpi.com
The gut is the body's largest immune organ, and the intestinal barrier prevents harmful
substances such as bacteria and toxins from passing through the gastrointestinal mucosa …