Listeria monocytogenes is a Gram-positive facultative intracellular pathogen that can cause
severe invasive infections upon ingestion with contaminated food. Clinically, listerial …

Importance Bacterial meningitis is a worldwide health problem, with incidence rates ranging
from approximately 0.9 per 100 000 individuals per year in high-income countries to 80 per …

The pathogenic bacterium Streptococcus pneumoniae (S. pneumoniae) can invade the
cerebrospinal fluid (CSF) and cause meningitis with devastating consequences. Whether …

Importance Hearing loss is a global social burden. Early identification of hearing loss missed
by newborn hearing screening tests in the neonatal intensive care unit is crucial. Objective …

To gain access to the brain, a so-called immune-privileged organ due to its physical
separation from the blood stream, pathogens and particularly viruses have been selected …

Pneumolysin is a major virulence factor of Streptococcus pneumoniae that plays a key role
in interaction with the host during invasive disease. How pneumolysin influences these …

The gastrointestinal tract contains trillions of microorganisms that exist symbiotically with the
host due to a tolerant, regulatory cell–rich intestinal immune system. However, this intimate …

We read with interest the recent meta-analysis assessing the clinical efficacy and safety of
nirmatrelvir plus ritonavir (NMV-r) in the treatment of patients with COVID-19. 1 Based on the …

Abstract Background The World Health Organization (WHO) reported an outbreak of
monkeypox virus (MPXV) in Western countries on May 12 th, 2022. In early October, WHO …

Background Patients with bacterial meningitis can be severely ill necessitating intensive
care unit (ICU) treatment. Here, we describe clinical features and prognostic factors of adults …