This MiniReview reports the current knowledge about the treatment of arterial hypertension
with the third‐generation beta‐adrenoceptor antagonist (BAA) nebivolol. Furthermore, it …

Our past study showed that coronary arterioles isolated from adipose-derived stromal
vascular fraction (SVF)–treated rats showed amelioration of the age-related decrease in …

Regulating blood cholesterol (Chol) levels by pharmacotherapy has successfully improved
cardiovascular health. There is growing interest in the role of Chol precursors in the …

Objective: This review covers the pharmacokinetics and pharmacodynamic of β-blockers,
the rationale for their use, some recent controversies in its use for managing hypertension …

Background. Some antihypertensive medications alter cellular energy production,
presumably by modification of the mitochondrial function. In vivo studies of such effects are …

In patients with hypertension, the triad represented by endothelial dysfunction, platelet
hyperactivity, and altered fibrinolytic function disturbs the equilibrium between hemostasis …

β 受体阻滞剂是常用的抗高血压药之一, 该类药物对β 受体的选择性存在明显差异.
奈必洛尔为第三代β 受体阻滞剂, 作用机制独特. 本文通过对奈必洛尔近年在降压方面的临床 …

Dear Editor, optimization of tissue perfusion is one of the primary goals of peri operative care
and its adequacy is of ten assumed based on systemic mea sures, such as mean arterial …

Numerous studies have demonstrated that sympathetic nervous system overactivation
during exercise in hypertensive rodents and humans is due, in part, to an exaggerated reflex …

为了手性合成新型β 受体阻断药Nebivolo, 通过对文献路线的分析, 基于经济高效的原则,
选择了一条合理的合成路线, 分别以廉价的维生素C 和D-甘露醇作为手性源 …