In vitro models of the blood–cerebrospinal fluid barrier and their applications in the development and research of (Neuro) Pharmaceuticals
F Dabbagh, H Schroten, C Schwerk - Pharmaceutics, 2022 - mdpi.com
The pharmaceutical research sector has been facing the challenge of neurotherapeutics
development and its inherited high-risk and high-failure-rate nature for decades. This hurdle …
development and its inherited high-risk and high-failure-rate nature for decades. This hurdle …
Breaking the barrier: in vitro models to study choroid plexus development
L Pellegrini, MA Lancaster - Current Opinion in Cell Biology, 2021 - Elsevier
The choroid plexus is central to normal brain function by secreting cerebrospinal fluid and
dynamically regulating its composition throughout development and homoeostasis. Much of …
dynamically regulating its composition throughout development and homoeostasis. Much of …
Organoid Technologies for SARS-CoV-2 Research
K Sutton, T Leach, V Surendran, P Clapp… - Current Stem Cell …, 2022 - Springer
Abstract Purpose of Review Organoids are an emerging technology utilizing three-
dimensional (3D), multi-cellular in vitro models to represent the function and physiological …
dimensional (3D), multi-cellular in vitro models to represent the function and physiological …
In vitro models of the choroid plexus and the blood-cerebrospinal fluid barrier: advances, applications, and perspectives
C Schwerk, H Schroten - Human Cell, 2024 - Springer
The choroid plexus (CP), a highly vascularized endothelial–epithelial convolute, is placed in
the ventricular system of the brain and produces a large part of the cerebrospinal fluid (CSF) …
the ventricular system of the brain and produces a large part of the cerebrospinal fluid (CSF) …
[图书][B] The Role of Betaine Focused Fluid Osmoregulation in Syringomyelia Post Spinal Cord Injury
DD Pukale - 2022 - search.proquest.com
Syringomyelia (SM) is a neurological disorder in which a fluid-filled cyst (syrinx) inside the
spinal cord forms due to either congenital or acquired (spinal cord injury (SCI)) causes. SM …
spinal cord forms due to either congenital or acquired (spinal cord injury (SCI)) causes. SM …