[HTML][HTML] MicroRNA-26a: an emerging regulator of renal biology and disease

X Li, X Pan, X Fu, Y Yang, J Chen, W Lin - Kidney and Blood Pressure …, 2019 - karger.com
MicroRNAs (miRNAs) are short, single-stranded, noncoding RNAs that modulate many key
biological processes by simultaneously suppressing multiple target genes. Among them …

[HTML][HTML] The long noncoding RNA LOC105374325 causes podocyte injury in individuals with focal segmental glomerulosclerosis

S Hu, R Han, J Shi, X Zhu, W Qin, C Zeng… - Journal of Biological …, 2018 - ASBMB
Focal segmental glomerulosclerosis (FSGS) is a common kidney disease that results in
nephrotic syndrome. FSGS arises from dysfunction and apoptosis of podocytes in the …

Autophagy is involved in mouse kidney development and podocyte differentiation regulated by Notch signalling

C Zhang, W Li, J Wen, Z Yang - Journal of Cellular and …, 2017 - Wiley Online Library
Podocyte dysfunction results in glomerular diseases accounted for 90% of end‐stage kidney
disease. The evolutionarily conserved Notch signalling makes a crucial contribution in …

DIANA-mirExTra v2. 0: Uncovering microRNAs and transcription factors with crucial roles in NGS expression data

IS Vlachos, T Vergoulis… - Nucleic acids …, 2016 - academic.oup.com
Differential expression analysis (DEA) is one of the main instruments utilized for revealing
molecular mechanisms in pathological and physiological conditions. DIANA-mirExTra v2. 0 …

[HTML][HTML] miR-200 family promotes podocyte differentiation through repression of RSAD2

Z Li, H Yin, S Hao, L Wang, J Gao, X Tan, Z Yang - Scientific reports, 2016 - nature.com
Mature podocytes are highly differentiated cells with several characteristic phenotypic
features that are involved in the glomerular filtration function. During kidney development, a …

[HTML][HTML] Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates

T Sato, K Kataoka, Y Ito, S Yokoyama, M Inui, M Mori… - Elife, 2020 - elifesciences.org
The body plan along the anteroposterior axis and regional identities are specified by the
spatiotemporal expression of Hox genes. Multistep controls are required for their unique …

Integrative analysis of microRNA and mRNA expression profiles in MARC-145 cells infected with PRRSV

Z Liang, L Wang, H Wu, D Singh, X Zhang - Virus genes, 2020 - Springer
Porcine reproductive and respiratory syndrome virus (PRRSV) causes tremendous
economic losses to the swine industry worldwide. miRNAs are crucial regulators of gene …

Computational Challenges and-omics Approaches for the Identification of microRNAs and Targets

IS Vlachos, G Georgakilas, S Tastsoglou… - Essentials of Noncoding …, 2017 - Elsevier
From very early on, computational methods have been deemed as key players in microRNA
(miRNA) research. Currently, there are numerous implemented approaches that can be …