[HTML][HTML] Neutrophils in chronic inflammatory diseases
A Herrero-Cervera, O Soehnlein… - Cellular & molecular …, 2022 - nature.com
Chronic inflammation is a component of many disease conditions that affect a large group of
individuals worldwide. Chronic inflammation is characterized by persistent, low-grade …
individuals worldwide. Chronic inflammation is characterized by persistent, low-grade …
Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease–novel insights into cellular communication circuits
Non-alcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease and is
emerging as the leading cause of cirrhosis, liver transplantation and hepatocellular …
emerging as the leading cause of cirrhosis, liver transplantation and hepatocellular …
[HTML][HTML] Crosstalk between oxidative stress and inflammatory liver injury in the pathogenesis of alcoholic liver disease
Alcoholic liver disease (ALD) is characterized by the injury, inflammation, and scarring in the
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
liver owing to excessive alcohol consumption. Currently, ALD is a leading cause for liver …
[HTML][HTML] Immunological mechanisms and therapeutic targets of fatty liver diseases
Alcoholic liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD) are the two major
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …
types of chronic liver disease worldwide. Inflammatory processes play key roles in the …
[HTML][HTML] Neutrophils in liver diseases: pathogenesis and therapeutic targets
K Liu, FS Wang, R Xu - Cellular & molecular immunology, 2021 - nature.com
Previously, it was assumed that peripheral neutrophils are a homogeneous population that
displays antimicrobial functions. However, recent data have revealed that neutrophils are …
displays antimicrobial functions. However, recent data have revealed that neutrophils are …
[HTML][HTML] Neutrophil-to-hepatocyte communication via LDLR-dependent miR-223–enriched extracellular vesicle transfer ameliorates nonalcoholic steatohepatitis
Neutrophil infiltration around lipotoxic hepatocytes is a hallmark of nonalcoholic
steatohepatitis (NASH); however, how these 2 types of cells communicate remains obscure …
steatohepatitis (NASH); however, how these 2 types of cells communicate remains obscure …
[HTML][HTML] Distinct histopathological phenotypes of severe alcoholic hepatitis suggest different mechanisms driving liver injury and failure
Intrahepatic neutrophil infiltration has been implicated in severe alcoholic hepatitis (SAH)
pathogenesis; however, the mechanism underlying neutrophil-induced injury in SAH …
pathogenesis; however, the mechanism underlying neutrophil-induced injury in SAH …
Immune–metabolic interactions in homeostasis and the progression to NASH
JA Hoogerland, B Staels, D Dombrowicz - Trends in Endocrinology & …, 2022 - cell.com
The incidence of non-alcoholic fatty liver disease (NAFLD) has increased significantly over
the past two decades. NAFLD ranges from simple steatosis (NAFL) to nonalcoholic …
the past two decades. NAFLD ranges from simple steatosis (NAFL) to nonalcoholic …
Immunopathobiology and therapeutic targets related to cytokines in liver diseases
Chronic liver injury with any etiology can progress to fibrosis and the end-stage diseases
cirrhosis and hepatocellular carcinoma. The progression of liver disease is controlled by a …
cirrhosis and hepatocellular carcinoma. The progression of liver disease is controlled by a …
[HTML][HTML] Sparcl1 promotes nonalcoholic steatohepatitis progression in mice through upregulation of CCL2
Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of chronic liver disease
ranging from simple steatosis (NAFL) to nonalcoholic steatohepatitis (NASH). However, the …
ranging from simple steatosis (NAFL) to nonalcoholic steatohepatitis (NASH). However, the …