Hypopituitarism

M Fleseriu, M Christ-Crain, F Langlois, M Gadelha… - The Lancet, 2024 - thelancet.com
Partial or complete deficiency of anterior or posterior pituitary hormone production leads to
central hypoadrenalism, central hypothyroidism, hypogonadotropic hypogonadism, growth …

Neuro-ophthalmic evaluation and management of pituitary disease

MTM Wang, JA Meyer, HV Danesh-Meyer - Eye, 2024 - nature.com
Neuro-ophthalmic evaluation is a crucial component of the diagnostic and prognostic
assessment of pituitary disease and compressive chiasmopathy, and can inform the timing …

Differences Between GH-and PRL-Cosecreting and GH-Secreting Pituitary Adenomas: a Series of 604 Cases

M Araujo-Castro, B Biagetti… - The Journal of …, 2024 - academic.oup.com
Context Few data exist about the clinical course of acromegaly, surgical and medical
outcomes in patients with GH-and prolactin cosecreting pituitary adenomas (GH&PRL-PAs) …

Consensus guideline for the diagnosis and management of pituitary adenomas in childhood and adolescence: Part 2, specific diseases

M Korbonits, JC Blair, A Boguslawska, J Ayuk… - Nature Reviews …, 2024 - nature.com
Pituitary adenomas are rare in children and young people under the age of 19 (hereafter
referred to as CYP) but they pose some different diagnostic and management challenges in …

Evidence-based definition of hypoprolactinemia in European men aged 40–86 years: the European male ageing study

TS Han, L Antonio, G Bartfai, TW O'Neill… - Reviews in Endocrine …, 2024 - Springer
Empirical evidence for a low normal or reference interval for serum prolactin (PRL) is lacking
for men, while the implications of very low PRL levels for human health have never been …

A proposed clinical classification for pituitary neoplasms to guide therapy and prognosis

KKY Ho, M Fleseriu, J Wass, L Katznelson… - The Lancet Diabetes & …, 2024 - thelancet.com
No comprehensive classification system that guides prognosis and therapy of pituitary
adenomas exists. The 2022 WHO histopathology-based classification system can only be …

Reply to 'The shift of therapeutic strategy for prolactinomas: surgery as the first-line option'

S Petersenn, M Fleseriu, S Melmed - Nature Reviews Endocrinology, 2024 - nature.com
Consensus Statement. Nat. Rev. Endocrinol. 19, 722–740 (2023) 1) in their
Correspondence (Wu, ZB The shift of therapeutic strategy for prolactinomas: surgery as the …

High prevalence of morphometric vertebral fractures opportunistically detected on thoracic radiograms in patients with non-functioning pituitary adenoma

S Frara, MM Uygur, F Bolamperti, L di Filippo, M Doga… - Pituitary, 2024 - Springer
Abstract Purpose Vertebral fractures (VFs), the hallmark of skeletal fragility, have been
reported as an emerging complication in patients with pituitary diseases associated with …

Diagnosing and treating the elderly individual with hypopituitarism

A Corsello, RM Paragliola, R Salvatori - Reviews in Endocrine and …, 2023 - Springer
Hypopituitarism in the elderly is an underestimated condition mainly due to the non-specific
presentation that can be attributed to the effects of aging and the presence of comorbidities …

Insights in hyperprolactinemia

MM Pineyro, SB Rulli, G Tamagno - Frontiers in Endocrinology, 2024 - frontiersin.org
Hyperprolactinemia is the most common endocrine disorder of the hypothalamicpituitary
axis. Prolactin is synthesized by the anterior pituitary lactotroph cells and is regulated by …