Mitochondrial calcium exchange in physiology and disease
JF Garbincius, JW Elrod - Physiological reviews, 2022 - journals.physiology.org
The uptake of calcium into and extrusion of calcium from the mitochondrial matrix is a
fundamental biological process that has critical effects on cellular metabolism, signaling …
fundamental biological process that has critical effects on cellular metabolism, signaling …
Mitochondrial calcium: effects of its imbalance in disease
D Matuz-Mares, M González-Andrade… - Antioxidants, 2022 - mdpi.com
Calcium is used in many cellular processes and is maintained within the cell as free calcium
at low concentrations (approximately 100 nM), compared with extracellular (millimolar) …
at low concentrations (approximately 100 nM), compared with extracellular (millimolar) …
Determinants, maintenance, and function of organellar pH
SA Freeman, S Grinstein… - Physiological reviews, 2023 - journals.physiology.org
The protonation state of soluble and membrane-associated macromolecules dictates their
charge, conformation, and functional activity. In addition, protons (H+ or their equivalents) …
charge, conformation, and functional activity. In addition, protons (H+ or their equivalents) …
The mitochondrial permeability transition pore: an evolving concept critical for cell life and death
G Morciano, N Naumova, P Koprowski… - Biological …, 2021 - Wiley Online Library
In this review, we summarize current knowledge of perhaps one of the most intriguing
phenomena in cell biology: the mitochondrial permeability transition pore (mPTP). This …
phenomena in cell biology: the mitochondrial permeability transition pore (mPTP). This …
Optical/electrochemical methods for detecting mitochondrial energy metabolism
W Ji, X Tang, W Du, Y Lu, N Wang, Q Wu… - Chemical Society …, 2022 - pubs.rsc.org
This review highlights the biological importance of mitochondrial energy metabolism and the
applications of multiple optical/electrochemical approaches to determine energy …
applications of multiple optical/electrochemical approaches to determine energy …
TMBIM5 is the Ca2+/H+ antiporter of mammalian mitochondria
Mitochondrial Ca2+ ions are crucial regulators of bioenergetics and cell death pathways.
Mitochondrial Ca2+ content and cytosolic Ca2+ homeostasis strictly depend on Ca2+ …
Mitochondrial Ca2+ content and cytosolic Ca2+ homeostasis strictly depend on Ca2+ …
ATAD3A has a scaffolding role regulating mitochondria inner membrane structure and protein assembly
T Arguello, S Peralta, H Antonicka, G Gaidosh, F Diaz… - Cell reports, 2021 - cell.com
Summary The ATPase Family AAA Domain Containing 3A (ATAD3A), is a mitochondrial
inner membrane protein conserved in metazoans. ATAD3A has been associated with …
inner membrane protein conserved in metazoans. ATAD3A has been associated with …
Pyrenoid proteomics reveals independent evolution of the CO2-concentrating organelle in chlorarachniophytes
R Moromizato, K Fukuda, S Suzuki… - Proceedings of the …, 2024 - National Acad Sciences
Pyrenoids are microcompartments that are universally found in the photosynthetic plastids of
various eukaryotic algae. They contain ribulose-1, 5-bisphosphate carboxylase/oxygenase …
various eukaryotic algae. They contain ribulose-1, 5-bisphosphate carboxylase/oxygenase …
Regulation of Mitochondrial Ca2+ Uptake
E Murphy, C Steenbergen - Annual review of physiology, 2021 - annualreviews.org
Mitochondria are responsible for ATP production but are also known as regulators of cell
death, and mitochondrial matrix Ca2+ is a key modulator of both ATP production and cell …
death, and mitochondrial matrix Ca2+ is a key modulator of both ATP production and cell …