Fast-spiking parvalbumin (PV) interneurons are inhibitory interneurons with unique
morphological and functional properties that allow them to precisely control local circuitry …

While great progress has been made in the understanding of neurological illnesses, the
pathologies, and etiologies that give rise to these diseases still remain an enigma, thus, also …

The resolution and dimensionality with which biologists can characterize cell types have
expanded dramatically in recent years, and intersectional consideration of such features (eg …

The array of whiskers on the snout provides rodents with tactile sensory information relating
to the size, shape and texture of objects in their immediate environment. Rodents can use …

Mouse primary somatosensory barrel cortex (wS1) processes whisker sensory information,
receiving input from two distinct thalamic nuclei. The first-order ventral posterior medial …

Neuroanatomical tracing methods remain fundamental for elucidating the complexity of
brain circuits. During the past decades, the technical arsenal at our disposal has been …

Identification of structural connections between neurons is a prerequisite to understanding
brain function. Here we developed a pipeline to systematically map brain-wide …

Extensive hierarchical yet highly reciprocal interactions among cortical areas are
fundamental for information processing. However, connectivity rules governing the …

Thalamo-cortical networks are central to seizures, yet it is unclear how these circuits initiate
seizures. We test whether a facial region of the thalamus, the ventral posteromedial nucleus …

Pain is a complex perceptual phenomenon. Coordinated activity among local and distant
brain networks is a central element of the neural underpinnings of pain. Brain oscillatory …