High-grade serous ovarian cancer (HGSOC) accounts for 70–80% of ovarian cancer deaths,
and overall survival has not changed significantly for several decades. In this Opinion article …

Triple-negative breast cancer (TNBC) is defined as a type of breast cancer with lack of
expression of estrogen receptor (ER), progesterone receptor (PR) and HER2 protein. The …

P53 immunohistochemistry has evolved into an accurate surrogate reflecting the underlying
TP53 mutation status of a tumor, and has utility in the diagnostic workup of endometrial …

Purpose Histologic transformation of EGFR mutant lung adenocarcinoma (LADC) into small-
cell lung cancer (SCLC) has been described as one of the major resistant mechanisms for …

TP53 mutations are ubiquitous in high‐grade serous ovarian carcinomas (HGSOC), and the
presence of TP53 mutation discriminates between high and low‐grade serous carcinomas …

Ovarian cancer is the fifth cause of cancer-related death in women and comprises a
histologically and genetically broad range of tumours, including those of epithelial, sex cord …

Endometrial cancer is a clinically heterogeneous disease and it is becoming increasingly
clear that this heterogeneity may be a function of the diversity of the underlying molecular …

A new paradigm for the pathogenesis of ovarian cancer has recently been proposed which
helps to explain persistent problems in describing the development and diverse morphology …

Reprogramming of amino acid metabolism, sustained by oncogenic signaling, is crucial for
cancer cell survival under nutrient limitation. Here we discovered that missense mutant p53 …

Canine mammary tumors (CMTs) are the most common neoplasm in intact female dogs.
Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the …