Early screening and diagnosis strategies of pancreatic cancer: a comprehensive review

J Yang, R Xu, C Wang, J Qiu, B Ren… - Cancer …, 2021 - Wiley Online Library
Pancreatic cancer is a highly malignant digestive system tumor with a poor prognosis. Most
pancreatic cancer patients are diagnosed at an advanced stage or even metastasis due to …

Pancreatic ductal adenocarcinoma: current and evolving therapies

A Adamska, A Domenichini, M Falasca - International journal of molecular …, 2017 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC), which constitutes 90% of pancreatic cancers, is
the fourth leading cause of cancer-related deaths in the world. Due to the broad …

Microfluidic device (ExoChip) for on-chip isolation, quantification and characterization of circulating exosomes

SS Kanwar, CJ Dunlay, DM Simeone, S Nagrath - Lab on a Chip, 2014 - pubs.rsc.org
Membrane bound vesicles, including microvesicles and exosomes, are secreted by both
normal and cancerous cells into the extracellular space and in blood circulation. These …

MicroRNA array analysis finds elevated serum miR-1290 accurately distinguishes patients with low-stage pancreatic cancer from healthy and disease controls

A Li, J Yu, H Kim, CL Wolfgang, MI Canto… - Clinical cancer …, 2013 - AACR
Purpose: Our goal was to identify circulating micro RNA (miRNA) levels that could
distinguish patients with low-stage pancreatic cancer from healthy and disease controls …

[HTML][HTML] Maintenance of cancer stemness by miR-196b-5p contributes to chemoresistance of colorectal cancer cells via activating STAT3 signaling pathway

D Ren, B Lin, X Zhang, Y Peng, Z Ye, Y Ma, Y Liang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Emerging studies indicated that cancer stem cells represent a subpopulation of cells within
the tumor that is responsible for chemotherapeutic resistance. However, the underlying …

Early diagnosis of pancreatic cancer: challenges and new developments

S Kaur, MJ Baine, M Jain, AR Sasson… - Biomarkers in …, 2012 - Taylor & Francis
Pancreatic cancer is a lethal malignancy with its incidence almost equivalent to mortality.
The complex pathophysiology, absence of early diagnostic and prognostic markers and …

Circulating miR-483-3p and miR-21 is highly expressed in plasma of pancreatic cancer

M Abue, M Yokoyama, R Shibuya… - International …, 2014 - spandidos-publications.com
Several recent studies have revealed that microRNAs (miRNAs) have a role in
carcinogenesis and cancer development, and that it is stably detectable in plasma/serum …

MicroRNA in pancreatic cancer: from biology to therapeutic potential

M Rawat, K Kadian, Y Gupta, A Kumar, PSG Chain… - Genes, 2019 - mdpi.com
Pancreatic cancer is one of the most aggressive malignancies, accounting for more than
45,750 deaths annually in the US alone. The aggressive nature and late diagnosis of …

The emerging role of MIR-146A in the control of hematopoiesis, immune function and cancer

C Labbaye, U Testa - Journal of hematology & oncology, 2012 - Springer
MicroRNA (miRs) represent a class of small non-coding regulatory RNAs playing a major
role in the control of gene expression by repressing protein synthesis at the post …

The microRNA-183 cluster: the family that plays together stays together

S Dambal, M Shah, B Mihelich, L Nonn - Nucleic acids research, 2015 - academic.oup.com
Abstract The microRNA (miR) 183 cluster, which is comprised of miRs-183,-96 and-182, is
also a miR family with sequence homology. Despite the strong similarity in the sequences of …