Parkinson's disease is a recognisable clinical syndrome with a range of causes and clinical
presentations. Parkinson's disease represents a fast-growing neurodegenerative condition; …

The development of interventions to slow or halt the progression of Parkinson's disease
remains a priority for patients and researchers alike. To date, no agents have been shown to …

Patients with isolated rapid-eye-movement sleep behaviour disorder (RBD) are commonly
regarded as being in the early stages of a progressive neurodegenerative disease involving …

Several studies have confirmed the α-synuclein real-time quaking-induced conversion (RT-
QuIC) assay to have high sensitivity and specificity for Parkinson's disease. However …

Objective This multilanguage study used simple speech recording and high‐end pattern
analysis to provide sensitive and reliable noninvasive biomarkers of prodromal versus …

Digital health technologies enable remote and therefore frequent measurement of motor
signs, potentially providing reliable and valid estimates of motor sign severity and …

The past decade has seen a dramatic expansion of the field of prodromal PD. Ten years
ago, there were only six known prodromal markers of disease, none of which had more than …

Introduction Parkinson's disease (PD) is characterized by specific voice disorders
collectively termed hypokinetic dysarthria. We here investigated voice changes by using …

The unmet timely diagnosis requirements, that take place years after substantial neural loss
and neuroperturbations in neuropsychiatric disorders, affirm the dire need for biomarkers …

Background and purpose Recent findings suggest that a gait assessment at a discrete
moment in a clinic or laboratory setting may not reflect functional, everyday mobility. As a …