Circulating tumor DNA in B-cell lymphoma: technical advances, clinical applications, and perspectives for translational research
EM Lauer, J Mutter, F Scherer - Leukemia, 2022 - nature.com
Noninvasive disease monitoring and risk stratification by circulating tumor DNA (ctDNA)
profiling has become a potential novel strategy for patient management in B-cell lymphoma …
profiling has become a potential novel strategy for patient management in B-cell lymphoma …
Genomic profiling for clinical decision making in lymphoid neoplasms
L De Leval, AA Alizadeh, PL Bergsagel… - Blood, The Journal …, 2022 - ashpublications.org
With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …
sequencing technologies, the genomic features of most lymphoid neoplasms have been …
[HTML][HTML] Determinants of resistance to engineered T cell therapies targeting CD19 in large B cell lymphomas
Most relapsed/refractory large B cell lymphoma (r/rLBCL) patients receiving anti-CD19
chimeric antigen receptor (CAR19) T cells relapse. To characterize determinants of …
chimeric antigen receptor (CAR19) T cells relapse. To characterize determinants of …
Distinct Hodgkin lymphoma subtypes defined by noninvasive genomic profiling
The scarcity of malignant Hodgkin and Reed–Sternberg cells hampers tissue-based
comprehensive genomic profiling of classic Hodgkin lymphoma (cHL). By contrast, liquid …
comprehensive genomic profiling of classic Hodgkin lymphoma (cHL). By contrast, liquid …
Circulating tumor DNA profiling for detection, risk stratification, and classification of brain lymphomas
JA Mutter, SK Alig, MS Esfahani, EM Lauer… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Clinical outcomes of patients with CNS lymphomas (CNSLs) are remarkably
heterogeneous, yet identification of patients at high risk for treatment failure is challenging …
heterogeneous, yet identification of patients at high risk for treatment failure is challenging …
Molecular features encoded in the ctDNA reveal heterogeneity and predict outcome in high-risk aggressive B-cell lymphoma
L Meriranta, A Alkodsi, A Pasanen… - Blood, The Journal …, 2022 - ashpublications.org
Inadequate molecular and clinical stratification of the patients with high-risk diffuse large B-
cell lymphoma (DLBCL) is a clinical challenge hampering the establishment of personalized …
cell lymphoma (DLBCL) is a clinical challenge hampering the establishment of personalized …
Clinical applications of circulating tumor DNA in central nervous system lymphoma
AK Foerster, EM Lauer, F Scherer - Seminars in Hematology, 2023 - Elsevier
Detection and characterization of circulating tumor DNA (ctDNA) in body fluids has the
potential to revolutionize management of patients with lymphoma. Minimal access to …
potential to revolutionize management of patients with lymphoma. Minimal access to …
Concurrent pembrolizumab with AVD for untreated classic Hodgkin lymphoma
RC Lynch, CS Ujjani, C Poh, EH Warren… - Blood, The Journal …, 2023 - ashpublications.org
Concurrent administration of pembrolizumab with chemotherapy in untreated classic
Hodgkin lymphoma (CHL) has not been studied previously. To investigate this combination …
Hodgkin lymphoma (CHL) has not been studied previously. To investigate this combination …
Sequencing therapy in relapsed DLBCL
CR Flowers, OO Odejide - Hematology, 2022 - ashpublications.org
Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoid malignancy
worldwide, comprising approximately 30% of all lymphomas. Currently, 50% to 60% of …
worldwide, comprising approximately 30% of all lymphomas. Currently, 50% to 60% of …
Entirely noninvasive outcome prediction in central nervous system lymphomas using circulating tumor DNA
JM Heger, J Mattlener, J Schneider, P Gödel, N Sieg… - Blood, 2024 - ashpublications.org
State-of-the-art response assessment of central nervous system lymphoma (CNSL) by
magnetic resonance imaging is challenging and an insufficient predictor of treatment …
magnetic resonance imaging is challenging and an insufficient predictor of treatment …