A randomized controlled crossover trial of acute intermittent and continuous hypoxia exposure in mild–moderate obstructive sleep apnea: A feasibility study

S Zha, X Liu, H Chen, Y Hao, J Zhang… - Journal of Sleep …, 2024 - Wiley Online Library
In a prospective, randomized, controlled crossover study, we explored the effects of acute
intermittent hypoxia and acute continuous hypoxia on patients with mild–moderate …

[HTML][HTML] A reminder that experimentally induced intermittent hypoxia is an incomplete model of obstructive sleep apnea and its outcome measures

JH Mateika - Journal of Applied Physiology, 2019 - journals.physiology.org
For two to three decades many scientists and clinicians in the field of sleep medicine
believed that exposure to intermittent hypoxia leads to numerous detrimental outcomes …

Randomised, controlled crossover trial of intermittent and continuous transcutaneous electrical stimulation of the genioglossus muscle for obstructive sleep apnoea

X Wu, D Zhao, W Hu, Z Zheng, S Zha, Q Zhang, K Hu - Thorax, 2023 - thorax.bmj.com
Purpose Continuous transcutaneous electrical stimulation (CTES) of the genioglossus
muscle may benefit patients with obstructive sleep apnoea (OSA). However, the therapeutic …

Retinoic acid receptor alpha activation is necessary and sufficient for plasticity induced by recurrent central apnea

KM Braegelmann, A Meza, AE Agbeh… - Journal of Applied …, 2021 - journals.physiology.org
Reductions in respiratory-related synaptic inputs to inspiratory motor neurons initiate a form
of plasticity that proportionally enhances inspiratory motor output, even in the absence of …