Neuronal Cav3 channelopathies: recent progress and perspectives
P Lory, S Nicole, A Monteil - Pflügers Archiv-European Journal of …, 2020 - Springer
T-type, low-voltage activated, calcium channels, now designated Cav3 channels, are
involved in a wide variety of physiological functions, especially in nervous systems. Their …
involved in a wide variety of physiological functions, especially in nervous systems. Their …
Evolutionary origin of synapses and neurons–Bridging the gap
P Burkhardt, SG Sprecher - Bioessays, 2017 - Wiley Online Library
The evolutionary origin of synapses and neurons is an enigmatic subject that inspires much
debate. Non‐bilaterian metazoans, both with and without neurons and their closest relatives …
debate. Non‐bilaterian metazoans, both with and without neurons and their closest relatives …
High cell diversity and complex peptidergic signaling underlie placozoan behavior
F Varoqueaux, EA Williams, S Grandemange… - Current Biology, 2018 - cell.com
Placozoans, together with sponges, are the only animals devoid of a nervous system and
muscles, yet both respond to sensory stimulation in a coordinated manner. How behavioral …
muscles, yet both respond to sensory stimulation in a coordinated manner. How behavioral …
Neuropeptidergic integration of behavior in Trichoplax adhaerens, an animal without synapses
A Senatore, TS Reese… - Journal of Experimental …, 2017 - journals.biologists.com
Trichoplax adhaerens is a flat, millimeter-sized marine animal that adheres to surfaces and
grazes on algae. Trichoplax displays a repertoire of different feeding behaviors despite the …
grazes on algae. Trichoplax displays a repertoire of different feeding behaviors despite the …
Sodium action potentials in placozoa: Insights into behavioral integration and evolution of nerveless animals
Placozoa are small disc-shaped animals, representing the simplest known, possibly
ancestral, organization of free-living animals. With only six morphological distinct cell types …
ancestral, organization of free-living animals. With only six morphological distinct cell types …
The enigmatic Placozoa part 1: Exploring evolutionary controversies and poor ecological knowledge
B Schierwater, HJ Osigus, T Bergmann… - …, 2021 - Wiley Online Library
The placozoan Trichoplax adhaerens is a tiny hairy plate and more simply organized than
any other living metazoan. After its original description by FE Schulze in 1883, it attracted …
any other living metazoan. After its original description by FE Schulze in 1883, it attracted …
Evolution of animal neural systems
Nervous systems are among the most spectacular products of evolution. Their provenance
and evolution have been of interest and often the subjects of intense debate since the late …
and evolution have been of interest and often the subjects of intense debate since the late …
Divergent Ca2+/calmodulin feedback regulation of CaV1 and CaV2 voltage-gated calcium channels evolved in the common ancestor of Placozoa and Bilateria
Ca V 1 and Ca V 2 voltage-gated calcium channels evolved from an ancestral Ca V 1/2
channel via gene duplication somewhere near the stem animal lineage. The divergence of …
channel via gene duplication somewhere near the stem animal lineage. The divergence of …
Calmodulin regulates Cav3 T-type channels at their gating brake
Calcium (Ca v 1 and Ca v 2) and sodium channels possess homologous CaM-binding
motifs, known as IQ motifs in their C termini, which associate with calmodulin (CaM), a …
motifs, known as IQ motifs in their C termini, which associate with calmodulin (CaM), a …
A Na+ leak channel cloned from Trichoplax adhaerens extends extracellular pH and Ca2+ sensing for the DEG/ENaC family close to the base of Metazoa
Acid-sensitive ion channels belonging to the degenerin/epithelial sodium channel
(DEG/ENaC) family activate in response to extracellular protons and are considered unique …
(DEG/ENaC) family activate in response to extracellular protons and are considered unique …