WNT signaling is an elaborate and complex collection of signal transduction pathways
mediated by multiple signaling molecules. WNT signaling is critically important for …

Glioblastoma (GBM) is a highly malignant brain tumor characterized by a heterogeneous
population of genetically unstable and highly infiltrative cells that are resistant to …

Glioblastoma multiforme (GBM) is the deadliest form of brain tumor with a more than 90% 5‐
year mortality. GBM has a paltry median survival of 12.6 months attributed to the unique …

WNTs and their downstream effectors regulate proliferation, death, and migration and cell
fate decision. Deregulation of WNT signaling is associated with various cancers including …

Glioblastoma multiforme (GBM) is among the most incurable cancers. GBMs survival rate
has not markedly improved, despite new radical surgery protocols, the introduction of new …

Glioblastoma (GBM) is the most aggressive, deadliest, and most common brain malignancy
in adults. Despite the advances made in surgical techniques, radiotherapy and …

Wnt is a complex signaling pathway involved in the regulation of crucial biological functions
such as development, proliferation, differentiation and migration of cells, mainly stem cells …

The WNT signaling pathway has been of great interest to developmental biologists for
decades and has more recently become a central topic for study in cancer biology. It is vital …

Neurogenesis and tumorigenesis share signaling molecules/pathways involved in cell
proliferation, differentiation, migration, and death. Self-renewal of neural stem cells is a …

AXIN1, has been initially identified as a prominent antagonist within the WNT/β-catenin
signaling pathway, and subsequently unveiled its integral involvement across a diverse …