Transient receptor potential vanilloid 1 (TRPV1) is an ion channel expressed on sensory
neurons triggering an influx of cations. TRPV1 receptors function as homotetramers …

Chronic pain is caused by cellular damage with an obligatory inflammatory component. In
response to noxious stimuli, high levels of ATP leave according to their concentration …

Many transient receptor potential (TRP) channels respond to diverse stimuli and
conditionally conduct small and large cations. Such functional plasticity is presumably …

When a behavior repeatedly fails to achieve its goal, animals often give up and become
passive, which can be strategic for preserving energy or regrouping between attempts. It is …

Transient receptor potential (TRP) proteins form a superfamily Ca2+-permeable cation
channels regulated by a range of chemical and physical stimuli. Structural analysis of a …

Abstract Transient Receptor Potential channels from the vanilloid subfamily (TRPV) are a
group of cation channels modulated by a variety of endogenous stimuli as well as a range of …

The selectivity of ion channels is fundamental for their roles in electrical and chemical
signaling and in ion homeostasis. Although most ion channels exhibit stable ion selectivity …

Transient receptor potential vanilloid (TRPV) channels are activated by ligands and heat
and are involved in various physiological processes. In contrast to the architecturally related …

Maintaining plasma calcium levels within a narrow range is of vital importance for many
physiological functions. Therefore, calcium transport processes in the intestine, bone and …

Transient receptor potential (TRP) proteins are a large family of cation-selective channels,
surpassed in variety only by voltage-gated potassium channels. Detailed molecular …