Hypercholesterolemia is a frequent metabolic disorder associated with increased risk for
cardiovascular morbidity and mortality. In addition to its well‐known proatherogenic effect …

Ischaemic and pharmacological conditioning of the left ventricle is mediated by the
activation of signalling cascades, which finally converge at the mitochondria and reduce …

Background Lipid accumulation in the liver and pancreas is primarily caused by combined
hyperlipidemia. However, the effect of isolated hypercholesterolemia without …

Acute myocardial infarction, often associated with ischemia/reperfusion injury (I/R), is a
leading cause of death worldwide. Although the endogenous tryptophan metabolite …

Aims Exogenously administered biglycan (core protein with high-molecular weight
glycosaminoglycan chains) has been shown to protect neonatal cardiomyocytes against …

Ventricular fibrillation (VF)-induced cardiac arrest frequently complicates ST-segment
elevation myocardial infarction (STEMI). Although larger infarct sizes (IS) correlate with a …

Electrical muscle stimulation (EMS) is a widely used method in sports and rehabilitation
therapies to simulate physical exercise. EMS treatment via skeletal muscle activity improves …

Calcitonin gene-related peptide (CGRP) may participate in ischemic post-conditioning
(IPost) attenuating myocardial ischemia/reperfusion injury. However, the molecular …

We and others have demonstrated a protective effect of pacing postconditioning (PPC)
against ischemia/reperfusion (I/R) injury. However, the mechanisms underlying this …

Ischemic preconditioning (IPre) reduces ischemia/reperfusion (I/R) injury in the heart. The
non-coding microRNA miR-125b-1-3p has been demonstrated to play a role in the …