Background The discovery of somatostatin (SST) and the synthesis of a variety of analogues
constituted a major therapeutic advance in the treatment of gastroenteropancreatic …

Most diseases that cause catastrophic loss of vision do so as a result of abnormal
angiogenesis and wound healing, often in response to tissue ischemia or inflammation …

Purpose Effective systemic therapy for advanced carcinoid is lacking. The combination of
bevacizumab (BEV) and pegylated (PEG) interferon alfa-2b was evaluated among patients …

Background There is a need for novel antitumor agents that demonstrate efficacy in currently
refractory tumors without adding to the toxicity of therapy. The somatostatin analogs, which …

Angiogenesis is the process of new blood vessel development from preexisting vasculature.
Although vascular endothelium is usually quiescent in the adult, active angiogenesis has …

Angiogenesis, or new blood vessel formation, is now known to play an important role in both
growth and metastasis of many cancers. The central importance of angiogenesis and the …

Somatostatin and its analogues bind to somatostatin receptors (sst) 1 through 5 that are
overexpressed in neuroendocrine neoplasms such as gastroenteropancreatic (GEP) …

Unique among known human herpesviruses, Kaposi's sarcoma–associated herpesvirus
(KSHV or HHV-8) encodes chemokine-like proteins (vMIP-I and vMIP-II). vMIP-II was shown …

Angiogenesis, the process through which new blood vessels arise from preexisting ones, is
regulated by several “classic” factors, among which the most studied are vascular …

Angiogenesis, the development of new blood vessels is a crucial process both for tumor
growth and metastatic dissemination. Additionally, dysregulation in angiogenesis has been …