Selective laser sintering (SLS), a new chapter in the production of solid oral forms (SOFs) by 3D printing

YA Gueche, NM Sanchez-Ballester, S Cailleaux… - Pharmaceutics, 2021 - mdpi.com
3D printing is a new emerging technology in the pharmaceutical manufacturing landscape.
Its potential advantages for personalized medicine have been widely explored and …

Melt extrusion with poorly soluble drugs–An integrated review

MA Repka, S Bandari, VR Kallakunta, AQ Vo… - International journal of …, 2018 - Elsevier
Over the last few decades, hot melt extrusion (HME) has emerged as a successful
technology for a broad spectrum of applications in the pharmaceutical industry. As indicated …

A lower temperature FDM 3D printing for the manufacture of patient-specific immediate release tablets

TC Okwuosa, D Stefaniak, B Arafat, A Isreb… - Pharmaceutical …, 2016 - Springer
Purpose The fabrication of ready-to-use immediate release tablets via 3D printing provides a
powerful tool to on-demand individualization of dosage form. This work aims to adapt a …

Multifunctional role of polyvinylpyrrolidone in pharmaceutical formulations

Y Luo, Y Hong, L Shen, F Wu, X Lin - AAPS PharmSciTech, 2021 - Springer
Abstract Polyvinylpyrrolidone (PVP), a non-ionic polymer, has been employed in multifarious
fields such as paper, fibers and textiles, ceramics, and pharmaceutics due to its superior …

Immediate release 3D-printed tablets produced via fused deposition modeling of a thermo-sensitive drug

W Kempin, V Domsta, G Grathoff, I Brecht… - Pharmaceutical …, 2018 - Springer
Purpose Dissolution speeds of tablets printed via Fused Deposition Modeling (FDM) so far
are significantly lower compared to powder or granule pressed immediate release tablets …

[HTML][HTML] Synthesis and characterization of mesoporous SBA-15 and SBA-16 as carriers to improve albendazole dissolution rate

ME Adrover, M Pedernera, M Bonne, B Lebeau… - Saudi Pharmaceutical …, 2020 - Elsevier
Albendazole (ABZ, anti-parasitic active pharmaceutical ingredient) is a crystalline low water-
soluble drug, thus the dissolution rate in gastrointestinal fluids is limited. Consequently, the …

The need for restructuring the disordered science of amorphous drug formulations

K Edueng, D Mahlin, CAS Bergström - Pharmaceutical research, 2017 - Springer
The alarming numbers of poorly soluble discovery compounds have centered the efforts
towards finding strategies to improve the solubility. One of the attractive approaches to …

Hot melt extrusion versus spray drying: hot melt extrusion degrades albendazole

S Hengsawas Surasarang, JM Keen… - Drug development …, 2017 - Taylor & Francis
The purpose of this study was to enhance the dissolution properties of albendazole (ABZ) by
the use of amorphous solid dispersions. Phase diagrams of ABZ–polymer binary mixtures …

Analytical and computational methods for the estimation of drug-polymer solubility and miscibility in solid dispersions development

D Medarević, J Djuriš, P Barmpalexis, K Kachrimanis… - Pharmaceutics, 2019 - mdpi.com
The development of stable solid dispersion formulations that maintain desired improvement
of drug dissolution rate during the entire shelf life requires the analysis of drug-polymer …

Understanding the effect of energy density and formulation factors on the printability and characteristics of SLS Irbesartan tablets—Application of the decision tree …

M Madžarević, Đ Medarević, S Pavlović, B Ivković… - Pharmaceutics, 2021 - mdpi.com
Selective laser sintering (SLS) is a rapid prototyping technique for the production of three-
dimensional objects through selectively sintering powder-based layer materials. The aim of …