Methods of the large-scale production of extracellular vesicles
V Syromiatnikova, A Prokopeva… - International Journal of …, 2022 - mdpi.com
To date, extracellular vesicles (EVs) have been extensively investigated as potential
substitutes for cell therapy. Research has suggested their ability to overcome serious risks …
substitutes for cell therapy. Research has suggested their ability to overcome serious risks …
Exosomes as potential functional nanomaterials for tissue engineering
Y Yao, Y Jiang, J Song, R Wang, Z Li… - Advanced …, 2023 - Wiley Online Library
Exosomes are cell‐derived extracellular vesicles of 40–160 nm diameter, which carry
numerous biomolecules and transmit information between cells. They are used as functional …
numerous biomolecules and transmit information between cells. They are used as functional …
Clinical translation of extracellular vesicles
Extracellular vesicles (EVs) occur in a variety of bodily fluids and have gained recent
attraction as natural materials due to their bioactive surfaces, internal cargo, and role in …
attraction as natural materials due to their bioactive surfaces, internal cargo, and role in …
Stem cell-derived extracellular vesicles as new tools in regenerative medicine-immunomodulatory role and future perspectives
E Karnas, P Dudek, EK Zuba-Surma - Frontiers in immunology, 2023 - frontiersin.org
In the last few decades, the practical use of stem cells (SCs) in the clinic has attracted
significant attention in the regenerative medicine due to the ability of these cells to proliferate …
significant attention in the regenerative medicine due to the ability of these cells to proliferate …
The role of biomechanical stress in extracellular vesicle formation, composition and activity
W Thompson, ET Papoutsakis - Biotechnology Advances, 2023 - Elsevier
Extracellular vesicles (EVs) are cornerstones of intercellular communication with exciting
fundamental, clinical, and more broadly biotechnological applications. However, variability …
fundamental, clinical, and more broadly biotechnological applications. However, variability …
DNA nanomaterial‐empowered surface engineering of extracellular vesicles
X Yao, D He, P Wei, Z Niu, H Chen, L Li… - Advanced …, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are cell‐secreted biological nanoparticles that are critical
mediators of intercellular communication. They contain diverse bioactive components, which …
mediators of intercellular communication. They contain diverse bioactive components, which …
Exosomes: From basic research to clinical diagnostic and therapeutic applications in cancer
S Araujo-Abad, JM Berna, E Lloret-Lopez… - Cellular Oncology, 2024 - Springer
Cancer continues to pose a global threat despite potent anticancer drugs, often
accompanied by undesired side effects. To enhance patient outcomes, sophisticated …
accompanied by undesired side effects. To enhance patient outcomes, sophisticated …
Translational challenges and prospective solutions in the implementation of biomimetic delivery systems
Biomimetic delivery systems (BDSs), inspired by the intricate designs of biological systems,
have emerged as a groundbreaking paradigm in nanomedicine, offering unparalleled …
have emerged as a groundbreaking paradigm in nanomedicine, offering unparalleled …
Mesenchymal Stem Cell Culture within Perfusion Bioreactors Incorporating 3D‐Printed Scaffolds Enables Improved Extracellular Vesicle Yield with Preserved …
Extracellular vesicles (EVs) are implicated as promising therapeutics and drug delivery
vehicles in various diseases. However, successful clinical translation will depend on the …
vehicles in various diseases. However, successful clinical translation will depend on the …
Synergistic vesicle-vector systems for targeted delivery
With the immense progress in drug delivery systems (DDS) and the rise of nanotechnology,
challenges such as target specificity remain. The vesicle-vector system (VVS) is a delivery …
challenges such as target specificity remain. The vesicle-vector system (VVS) is a delivery …