Autism spectrum disorder (ASD) is a prevalent and complex neurodevelopmental disorder
which has strong genetic basis. Despite the rapidly rising incidence of autism, little is known …

Recent studies on mutations in cancer genomes have distinguished driver mutations from
passenger mutations, which occur as byproducts of cancer development. The cancer …

Women experience osteoporosis at higher rates than men. Aside from hormones, the
mechanisms driving sex-dependent bone mass regulation are not well understood. Here …

Our recent study has shown that prenatal exposure to bisphenol A (BPA) altered the
expression of genes associated with autism spectrum disorder (ASD). In this study, we …

Biological sex profoundly conditions organismal development and physiology, imposing
wide-ranging effects on cell signaling, metabolism, and immune response. These effects …

Emerging evidence suggested that epigenetic regulators can exhibit both activator and
repressor activities in gene transcriptional regulation and disease development, such as …

Social behavior, a highly adaptive and crucial component of mammalian life, is regulated by
particularly sensitive regulatory brain mechanisms. Substantial evidence implicates classical …

Autism spectrum disorder (ASD) is a constellation of neurodevelopmental disorders with
high phenotypic and genetic heterogeneity, complicating the discovery of causative genes …

Background Epigenetic mechanisms, including DNA methylation, microRNAs and histone
modifications, may modulate the genetic expression in migraine and its interaction with …

The complexity of biological sex differences is markedly evident in human physiology and
pathology. Although many of these differences can be ascribed to the expression of sex …