Noncovalent protein-ligand complexes are readily detected by electrospray ionization mass
spectrometry (ESI-MS). Ligand binding stoichiometry can be determined easily by the ESI …

An azobenzene-derived photoswitch has been covalently cross-linked to two sites of the S-
peptide in the RNase S complex in a manner that the α-helical content of the S-peptide …

Do the polarities of the N-terminus or the apolarity of the C-terminus of bovine RNase A
influence the relative yields of its two 3D domain-swapped dimeric conformers, the N-dimer …

Mass cytometry (MC) and imaging mass cytometry (IMCTM) have emerged as important
tools for the study of biological heterogeneity. We recently demonstrated the use of l‐2 …

Pyrrolidone carboxyl peptidases (PCPs) from hyperthermophiles have a structurally
conserved and completely buried Glu192 in the hydrophobic core; in contrast, the …

Background The tumour suppressor protein p53 protein has a core domain that binds DNA
and is the site for most oncogenic mutations. This domain is quite unstable compared to its …

The role played by the degree of folding of protein backbones in explaining the binding
energetics of protein− ligand interactions has been studied. We analyzed the protein/peptide …

By lyophilization from 40% acetic acid solutions, bovine ribonuclease A forms well
characterized, three-dimensional domain-swapped oligomers: dimers, trimers, tetramers …

Sažetak Neobične (ili rijetko korištene) aminokiseline su prisutne u nekolicini staničnih
peptida. Često su uključene u peptidne antibiotike proizvedene ne-ribosomalnom sintezom …