Regulated fibroblast growth factor (FGF) signalling is a prerequisite for the correct
development and homeostasis of articular cartilage, as evidenced by the fact that aberrant …

Fibroblast growth factors (FGFs) mediate a broad range of functions in both the developing
and adult organism. The accumulated wealth of structural information on the FGF signalling …

Chronic kidney disease (CKD) is a worldwide public health threat that increases risk of
death due to cardiovascular complications, including left ventricular hypertrophy (LVH) …

Fibroblast growth factor (FGF) 23 is a phosphaturic hormone whose physiologic actions on
target tissues are mediated by FGF receptors (FGFR) and klotho, which functions as a co …

In mammals, phosphate balance is maintained by influx and efflux via the intestines,
kidneys, bone, and soft tissue, which involves multiple sodium/phosphate (Na+/Pi) …

Abstract Fibroblast growth factor-23 (FGF23) is a bone-derived hormone protecting against
the potentially deleterious effects of hyperphosphatemia by suppression of phosphate …

Fibroblast growth factors (FGFs) signal in a paracrine or endocrine fashion to mediate a
myriad of biological activities, ranging from issuing developmental cues, maintaining tissue …

Fibroblast growth factors (FGF) constitute a large family of proteins with pleiotropic effects on
development, organogenesis, and metabolism. The FGF19 subclass includes growth factors …

Fibroblast growth factor-23 (FGF23) is a bone-derived hormone suppressing phosphate
reabsorption and vitamin D hormone synthesis in the kidney. At physiological concentrations …

Fibroblast growth factors (FGFs) are cell-signaling proteins with diverse functions in cell
development, repair, and metabolism. The human FGF family consists of 22 structurally …