Alterations in theta-gamma coupling and sharp wave-ripple, signs of prodromal hippocampal network impairment in the TgF344-AD rat model
Alzheimer's disease (AD) is a severe neurodegenerative disorder caused by the
accumulation of toxic proteins, amyloid-beta (Aβ) and tau, which eventually leads to …
accumulation of toxic proteins, amyloid-beta (Aβ) and tau, which eventually leads to …
Assessing rapid spatial working memory in community-living older adults in a virtual adaptation of the rodent water maze paradigm
EHJ Wang, FHY Lai, WM Leung, TY Shiu… - Behavioural Brain …, 2025 - Elsevier
Aging often leads to a decline in various cognitive domains, potentially contributing to spatial
navigation challenges among older individuals. While the Morris water maze is a common …
navigation challenges among older individuals. While the Morris water maze is a common …
Improving Translational Relevance in Preclinical Psychopharmacology (iTRIPP)
Animal models are important in preclinical psychopharmacology to study mechanisms and
potential treatments for psychiatric disorders. A working group of 14 volunteers, comprising …
potential treatments for psychiatric disorders. A working group of 14 volunteers, comprising …
Zero-phase-delay connectivity increases the reliability, concordance with structure, and prognostic ability of functional connectivity metrics
Zero-phase-delay synchrony between the activity of distant neural populations has been
robustly observed. Nevertheless, contemporary electroencephalography and …
robustly observed. Nevertheless, contemporary electroencephalography and …
Single trial characterization of frontal Theta and parietal Alpha oscillatory episodes during Spatial Navigation in humans
Theoretical proposals and empirical findings both highlight the relevance of Theta brain
oscillations in human Spatial Navigation. However, whilst the general assumption is that the …
oscillations in human Spatial Navigation. However, whilst the general assumption is that the …
The Neural Correlates of Spatial Learning and Memory During Human Navigation.
C Thornberry - 2024 - mural.maynoothuniversity.ie
Spatial navigation is an essential skill for animals and humans alike. It helps us get to a
desired place and remember how to get back there in the future. Despite the fact that this …
desired place and remember how to get back there in the future. Despite the fact that this …
Multimodal approach to unravel network disturbances and compensatory mechanisms during pre-and earlyplaque stages of Alzheimer's Disease
M van den Berg - 2023 - repository.uantwerpen.be
Due to the aging world population, the number of people that are suffering from Alzheimers
Disease (AD) is expected to dramatically increase. In AD, an accumulation of both toxic …
Disease (AD) is expected to dramatically increase. In AD, an accumulation of both toxic …
A link between NMDA receptor hypofunction and GABAergic inhibition in the modulation of cognition: a comparison of neural and cognitive changes in rat models of …
C Taylor - 2023 - eprints.nottingham.ac.uk
NMDA receptor (NMDAR) hypofunction and impaired GABAergic inhibition, so-called neural
disinhibition, in the hippocampus and prefrontal cortex, have both been implicated in the …
disinhibition, in the hippocampus and prefrontal cortex, have both been implicated in the …
[PDF][PDF] La experiencia del espacio-tiempo arquitectónico. Una perspectiva fenomenológica del sensorium
GS González, I Jiménez-Fajardo - Revista de Arquitectura, 2022 - scholar.archive.org
La arquitectura y los espacios urbanos ofrecen la experiencia espacial real y diversa, a
diferencia de la que otorgan los dispositivos o medios tecnológicos digitales. Por esta …
diferencia de la que otorgan los dispositivos o medios tecnológicos digitales. Por esta …