Cell proliferation is orchestrated through diverse proteins related to calcium (Ca 2+)
signaling inside the cell. Cellular Ca 2+ influx that occurs first by various mechanisms at the …

Chemotherapy using natural compounds, such as resveratrol, curcumin, paclitaxel,
docetaxel, etoposide, doxorubicin, and camptothecin, is of importance in cancer therapy …

Multidrug resistance (MDR) is the key cause that accounts for the failure of clinical cancer
chemotherapy. To address the problem, herein, we presented an alternative strategy to …

Cancer, the second cause of death worldwide, is characterized by several common criteria,
known as the “cancer hallmarks” such as unrestrained cell proliferation, cell death …

Ca2+ influx through Ca2+ permeable ion channels is a key trigger and regulator of a diverse
set of cellular events, such as neurotransmitter release and muscle contraction. Ca2+ influx …

Abstract Calcium ions (Ca2+) are indispensable and versatile metal ions that play a pivotal
role in regulating cell metabolism, encompassing cell survival, proliferation, migration, and …

Regulation of intracellular calcium is an important signaling mechanism for cell proliferation
in both normal and cancerous cells. In normal epithelial cells, free calcium concentration is …

Both increases in the basal cytosolic calcium concentration ([Ca2+] cyt) and [Ca2+] cyt
transients play major roles in cell cycle progression, cell proliferation and division. Calcium …

Electromagnetic field (EMF) exposures affect many biological systems. The reproducibility of
these effects is related to the intensity, duration, frequency, and pattern of the EMF. We have …

T-type calcium channels are involved in a multitude of cellular processes, both physiological
and pathological, including cancer. T-type channels are also often aberrantly expressed in …