During the past few years, crystallography of G protein–coupled receptors (GPCRs) has
experienced exponential growth, resulting in the determination of the structures of 16 distinct …

A great deal of experimental evidence suggests that ligands can stabilize different receptor
active states that go on to interact with cellular signaling proteins to form a range of different …

Co-evolution is a fundamental component of the theory of evolution and is essential for
understanding the relationships between species in complex ecological networks. A wide …

The interactions of chemokines with their G protein-coupled receptors promote the migration
of leukocytes during normal immune function and as a key aspect of the inflammatory …

Chemokines are critical mediators of cell migration during routine immune surveillance,
inflammation, and development. Chemokines bind to G protein–coupled receptors and …

Der ROMEIS ist seit fast 100 Jahren das Standardwerk der mikroskopischen Technik. Über
18 Auflagen hat dieses Methodenbuch die Entwicklung der lichtmikroskopischen Verfahren …

G protein‐coupled chemokine receptors and their peptidergic ligands are interesting
therapeutic targets due to their involvement in various immune‐related diseases, including …

The chemokines platelet factor 4 (PF4) and RANTES (regulated on activation normal T cell
expressed and secreted) are secreted by activated platelets and influence multiple cell types …

The idea that G-protein-coupled receptors (GPCRs) can function as dimers is now generally
accepted. Although an increasing amount of data suggests that dimers represent the basic …

The presence of two CXCL8 receptor types combined with the inflammatory roles of PMN
has led to interest in whether each receptor type contributes to unique functions. PMN are …