[HTML][HTML] Natural marine products: Anti-colorectal cancer in vitro and in vivo

N Han, J Li, X Li - Marine drugs, 2022 - mdpi.com
Colorectal cancer, a malignant tumor with high mortality, has a poor prognosis due to drug
resistance and toxicity in clinical surgery and chemotherapy. Thus, finding safer and more …

[HTML][HTML] Bioactive compounds from marine sponges and algae: effects on cancer cell metabolome and chemical structures

R Esposito, S Federico, F Glaviano, E Somma… - International Journal of …, 2022 - mdpi.com
Metabolomics represent the set of small organic molecules generally called metabolites,
which are located within cells, tissues or organisms. This new “omic” technology, together …

Vitis vinifera leaf extract liposomal Carbopol gel preparation's potential wound healing and antibacterial benefits: in vivo, phytochemical, and computational …

AH Elmaidomy, SA Mohamad, M Abdelnaser… - Food & Function, 2023 - pubs.rsc.org
Vitis vinifera Egyptian edible leaf extract loaded on a soybean lecithin, cholesterol, and
Carbopol gel preparation (VVL-liposomal gel) was prepared to maximize the in vivo wound …

Antiproliferative potential of Physalis peruviana-derived magnolin against pancreatic cancer: A comprehensive in vitro and in silico study

AM Sayed, SS El-Hawary, UR Abdelmohsen… - Food & Function, 2022 - pubs.rsc.org
Physalis peruviana L. is a common edible fruit in Egypt and other regional countries. In the
present study, we investigated its crude extract as a potential source of antiproliferative …

[HTML][HTML] Network Pharmacological Analysis of the Red Sea Sponge Hyrtios erectus Extract to Reveal Anticancer Efficacy of Corresponding Loaded Niosomes

HA Abou-Taleb, AM Sayed, H Refaat, F Alsenani… - Marine Drugs, 2022 - mdpi.com
In this study, the LC-HRMS-assisted chemical profiling of Hyrtios erectus sponge led to the
annotation of eleven major compounds (1–11). H. erectus-derived crude extract (HE) was …

[HTML][HTML] The Protective and Therapeutic Anti-Alzheimer Potential of Olea europaea L. cv. Picual: An In Silico and In Vivo Study

AA Bagalagel, SS El-Hawary, R Alaaeldin… - Metabolites, 2022 - mdpi.com
LC-HRESIMS metabolomic profiling of Olea europaea L. cv. Picual (OEP)(Saudi Arabian
olive cultivar, F. Oleacea) revealed 18 compounds. Using pharmacology networking to …

[HTML][HTML] Anti-Alzheimer potential of Solanum lycopersicum seeds: in vitro, in vivo, metabolomic, and computational investigations

HT Bakhsh, OH Abdelhafez, AH Elmaidomy… - Beni-Suef University …, 2024 - Springer
Abstract Background Solanum lycopersicum Linn.(Tomato, Family Solanaceae) is one of the
fruits that are most consumed worldwide. The current research intends to emphasise the …

[HTML][HTML] Bioactive Phytochemicals of Citrus reticulata Seeds—An Example of Waste Product Rich in Healthy Skin Promoting Agents

T Al-Warhi, AH Elmaidomy, S Selim, MM Al-Sanea… - Antioxidants, 2022 - mdpi.com
Phytochemical investigation of Egyptian mandarin orange (Citrus reticulata Blanco, F.
Rutaceae) seeds afforded thirteen known compounds, 1–13. The structures of isolated …

[HTML][HTML] Abelmoschus eculentus Seed Extract Exhibits In Vitro and In Vivo Anti-Alzheimer's Potential Supported by Metabolomic and Computational Investigation

HT Bakhsh, FA Mokhtar, AH Elmaidomy, HF Aly… - Plants, 2023 - mdpi.com
Abelmoschus esculentus Linn.(okra, F. Malvaceae) is a fruit widely consumed all over the
world. In our study, the anti-Alzheimer's potential of A. esculentus was evaluated. An in vitro …

[HTML][HTML] EGFR and COX-2 dual inhibitor: the design, synthesis, and biological evaluation of novel chalcones

A Musa, EM Mostafa, SNA Bukhari, NH Alotaibi… - Molecules, 2022 - mdpi.com
For most researchers, discovering new anticancer drugs to avoid the adverse effects of
current ones, to improve therapeutic benefits and to reduce resistance is essential. Because …