Sleep-mediated regulation of reward circuits: implications in substance use disorders

R Guo, DT Vaughan, ALA Rojo… - …, 2023 - nature.com
Our modern society suffers from both pervasive sleep loss and substance abuse—what may
be the indications for sleep on substance use disorders (SUDs), and could sleep contribute …

Exploring the possibility of a proprietary black cumin oil extract as a Dual Orexin Receptor Antagonist in restoring stress-sleep balance on stress-induced sleep …

OR Saneha, P Krishna, IM Krishnakumar, L Joseph - PharmaNutrition, 2023 - Elsevier
Background Orexins act as a molecular switch for the release of cortisol/corticosterone in
response to a stress stimulus and hence to regulate sleep/wake cycle. Orexin agonism …

Structural neuroplasticity after sleep loss modifies behavior and requires neurexin and neuroligin

MH Cowen, DM Raizen, MP Hart - Iscience, 2024 - cell.com
Structural neuroplasticity (changes in the size, strength, number, and targets of synaptic
connections) can be modified by sleep and sleep disruption. However, the causal …

Oxidative Stress Induces Endothelial Dysfunction and Endothelial Cell Damage in Rapid Eye Movement (REM) Sleep Deprivation Animal Model

L Noordin, A Nawi, AAM Zin… - IIUM Medical Journal …, 2022 - journals.iium.edu.my
INTRODUCTION: Rapid eye movement (REM) sleep deprivation causes oxidative stress,
leading to endothelial dysfunction, a predictor of cardiovascular disease. It is still unclear …

[PDF][PDF] The Neural Mechanisms of Sleep and Migraine

EC Stanyer - 2023 - kclpure.kcl.ac.uk
Whilst a bidirectional relationship between sleep and migraine has long been postulated,
this remains mainly speculative, and the underlying neural mechanisms remain to be …