Uncontrolled massive bleeding with subsequent derangement of the coagulation system is a
major challenge in the management of both surgical and seriously injured patients. Under …

Objectives We review the evidence for tranexamic acid (TXA) for the treatment and
prevention of bleeding caused by surgery, trauma and bleeding disorders. We highlight …

1 ESGE recommends in patients with acute upper gastrointestinal hemorrhage (UGIH) the
use of the Glasgow–Blatchford Score (GBS) for pre-endoscopy risk stratification. Patients …

This is the first UK national guideline to concentrate on acute lower gastrointestinal bleeding
(LGIB) and has been commissioned by the Clinical Services and Standards Committee of …

This article is part of a series of articles featuring the Catalogue of Bias introduced in this
volume of BMJ Evidence-Based Medicine that describes attrition bias and outlines its …

Perioperative bleeding remains a major complication during and after surgery, resulting in
increased morbidity and mortality. The principal causes of non-vascular sources of …

Men's health: COVID-19 pandemic highlights need for overdue policy action the effect of the
total number of adverse events would have been more precise and therefore easier to …

Tranexamic acid (TXA) is an effective hemostatic agent used for the reduction of blood loss
and transfusion. However, the safety profile of TXA remains in question due to a potential …

Tranexamic Acid - StatPearls - NCBI Bookshelf US flag An official website of the United States
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Upper gastrointestinal bleeding (UGIB), defined as intraluminal hemorrhage proximal to the
ligament of Treitz, can range from mild and asymptomatic to massive lifethreatening …