Mastocytosis is a heterogeneous group of neoplasms defined by a numerical increase and
accumulation of clonal mast cells (MCs) in various organ systems. The disease may present …

Abstract Disease Overview Chronic myelomonocytic leukemia (CMML) is a clonal
hematopoietic stem cell disorder with overlapping features of myelodysplastic syndromes …

The classification of myeloid neoplasms and acute leukemias was last updated in 2016
within a collaboration between the World Health Organization (WHO), the Society for …

Clonal cytopenia of undetermined significance (CCUS) is associated with an increased risk
of developing a myeloid neoplasm with myelodysplasia (MN). To identify the features of the …

Disease overview Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic
stem cell disorder with overlapping features of myelodysplastic syndromes and …

Abstract The International Consensus Classification (ICC) of myeloid neoplasms and acute
leukemia has updated the classification of myelodysplastic syndromes (MDSs) and placed …

Chronic myelomonocytic leukemia (CMML) is a myelodysplastic syndrome/
myeloproliferative overlap neoplasm characterized by sustained peripheral blood …

The myelodysplastic syndrome/myeloproliferative neoplasms (MDS/MPN) category includes
a heterogeneous group of diseases characterized by the co-occurrence of clinical and …

This article discusses the rationale for inclusion of flow cytometry (FCM) in the diagnostic
investigation and evaluation of cytopenias of uncertain origin and suspected …

The use of small molecules became one key cornerstone of targeted anti-cancer therapy.
Among them, tyrosine kinase inhibitors (TKIs) are especially important, as they were the first …