Zika virus: diagnostics for an emerging pandemic threat
JJ Waggoner, BA Pinsky - Journal of clinical microbiology, 2016 - Am Soc Microbiol
Zika virus (ZIKV) is an Aedes mosquito-borne flavivirus that emerged in Brazil in 2015 and
then rapidly spread throughout the tropical and subtropical Americas. Based on clinical …
then rapidly spread throughout the tropical and subtropical Americas. Based on clinical …
Dengue detection: advances in diagnostic tools from conventional technology to point of care
The dengue virus (DENV) is a vector-borne flavivirus that infects around 390 million
individuals each year with 2.5 billion being in danger. Having access to testing is paramount …
individuals each year with 2.5 billion being in danger. Having access to testing is paramount …
Field-deployable viral diagnostics using CRISPR-Cas13
Mitigating global infectious disease requires diagnostic tools that are sensitive, specific, and
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK …
rapidly field deployable. In this study, we demonstrate that the Cas13-based SHERLOCK …
Viremia and clinical presentation in Nicaraguan patients infected with Zika virus, chikungunya virus, and dengue virus
JJ Waggoner, L Gresh, MJ Vargas… - Clinical Infectious …, 2016 - academic.oup.com
Background. Zika virus (ZIKV), chikungunya virus (CHIKV), and dengue virus (DENV)
cocirculate in Nicaragua. In this study, we sought to compare the quantified viremia and …
cocirculate in Nicaragua. In this study, we sought to compare the quantified viremia and …
Global and cell type-specific immunological hallmarks of severe dengue progression identified via a systems immunology approach
Severe dengue (SD) is a major cause of morbidity and mortality. To define dengue virus
(DENV) target cells and immunological hallmarks of SD progression in children's blood, we …
(DENV) target cells and immunological hallmarks of SD progression in children's blood, we …
Homotypic dengue virus reinfections in Nicaraguan children
JJ Waggoner, A Balmaseda, L Gresh… - The Journal of …, 2016 - academic.oup.com
Background. Infection with any of the 4 related dengue virus serotypes (DENV-1–4) is
thought to result in lifelong immunity to homotypic reinfection (ie, reinfection with the same …
thought to result in lifelong immunity to homotypic reinfection (ie, reinfection with the same …
Performance of dengue diagnostic tests in a single-specimen diagnostic algorithm
EA Hunsperger, J Muñoz-Jordán… - The Journal of …, 2016 - academic.oup.com
Background. Anti–dengue virus (DENV) immunoglobulin M (IgM) seroconversion has been
the reference standard for dengue diagnosis. However, paired specimens are rarely …
the reference standard for dengue diagnosis. However, paired specimens are rarely …
A sensitive electrochemical method for rapid detection of dengue virus by CRISPR/Cas13a-assisted catalytic hairpin assembly
J Wang, Q Xia, J Wu, Y Lin, H Ju - Analytica Chimica Acta, 2021 - Elsevier
Dengue fever caused by Dengue virus (DENV) infection has been widely popular,
especially in tropical and subtropical areas. Rapid and sensitive diagnosis is the first priority …
especially in tropical and subtropical areas. Rapid and sensitive diagnosis is the first priority …
Comparison of four serological methods and two reverse transcription-PCR assays for diagnosis and surveillance of Zika virus infection
A Balmaseda, JV Zambrana, D Collado… - Journal of clinical …, 2018 - Am Soc Microbiol
Zika virus (ZIKV) is a mosquito-borne flavivirus that is responsible for recent explosive
epidemics in the Americas. Notably, ZIKV infection during pregnancy has been found to …
epidemics in the Americas. Notably, ZIKV infection during pregnancy has been found to …
[HTML][HTML] High dengue burden and circulation of 4 virus serotypes among children with undifferentiated fever, Kenya, 2014–2017
Little is known about the extent and serotypes of dengue viruses circulating in Africa. We
evaluated the presence of dengue viremia during 4 years of surveillance (2014–2017) …
evaluated the presence of dengue viremia during 4 years of surveillance (2014–2017) …